FRIEDELIN 98.5% high purity
559-74-0
Pharmaceutical Grade
98.5%
shanghai
bag
2022-12-31
chemicals,4-aminobenzenesulfonic acid,Cyclohexanone,N-cyclohexylcyclohexanamine,aluminum,propane-1,2-diol,trihypochlorite,hydrate,cumene hydroperoxide
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceFriedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively[1].
Friedelin is a pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork. It has a role as an anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and a plant metabolite. It is a pentacyclic triterpenoid and a cyclic terpene ketone.Basic Info-
Product Name:
Friedelin
Other Name:24,25,26-Trinoroleanan-3-one,5,9,13-trimethyl-,(4β,5β,8α,9β,10α,13α,14β)-;D:A-Friedooleanan-3-one;Friedelin;(4β,5β,8α,9β,10α,13α,14β)-5,9,13-Trimethyl-24,25,26-trinoroleanan-3-one;(-)-Friedelin;Friedelan-3-one;Friedeline;Friedelanone;3(2H)-Picenone,eicosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-,[4R-(4α,4aα,6aβ,6bα,8aα,12aα,12bβ,14aα,14bβ)]-;3(2H)-Picenone,eicosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-,(4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-;NSC 55141;3-Oxofriedelane
CAS No.:559-74-0
Molecular Formula:C30H50O
InChIKeys:InChIKey=OFMXGFHWLZPCFL-SVRPQWSVSA-N
Molecular Weight:426.72
Exact Mass:426.72
EC Number:209-205-1
UNII:AK21264UAD
Categories:
Characteristics-
PSA:
17.1
XLogP3:10.87
Density:1.0±0.1 g/cm3
Melting Point:263 °C
Boiling Point:477.2±13.0 °C at 760 mmHg
Flash Point:233.9±12.1 °C
Refractive Index:1.503
Storage Conditions:2-8°C
Specific rotation:D -27.8° (chloroform)
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
chemicals,4-aminobenzenesulfonic acid,Cyclohexanone,N-cyclohexylcyclohexanamine,aluminum,propane-1,2-diol,trihypochlorite,hydrate,cumene hydroperoxide
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Location:
E728,No.5 Yongzhi Rd., Baixia High-tech Zone
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
30
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2015
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Certifications:
ISO 45000,ISO 14000,ISO certificate
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