Native Human Carbonic Anhydrase I
4 Inquiries
9001-03-0
Yes
2026-11-23
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Details
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Seller Information
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Inquiry History
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Description
ProductName Native Human Carbonic Anhydrase I Cat No NATE-0097 Description Carbonic anhydrase is a zinc metalloenzyme that has a molecular weight of approximately 30 kDa Da. The enzyme catalyzes the hydRation of carbon dioxide to carbonic acid. It is involved in vital processes such as pH and CO2 homeostasis, transport of bicarbonate and CO2, biosynthetic reactions, bone resorption, calcification, and tumorigenicity. Therefore, this enzyme is an important target for inhibitors with clinical applications in various pathologies such as glaucoma, epilepsy and Parkinson’s disease. Abbr CA1, Native (Human) Alias CA-I; CA1 Source Human erythrocytes Species Human Applications Carbonic anhydrase from human erythrocytes (HCA) has been used to study the molten-globule state of carbonic anhydrase (CA). Chaperone-like α-crystallin binds to this state of the enzyme and prevents its aggregation. The enzyme from Creative Enzymes has been used for the analysis of thermodynamic stability of the enzyme. Furthermore, its clinical significance has been evaluated in human non-small cell lung cancer. Form powder Enzyme Commission Number EC 4.2.1.1 Activity 100-500 W-A units/mg protein CAS No 9001-03-0 Isoelectric point 6.6 Unit Definition One Wilbur-Anderson (W-A) unit will cause the pH of a 0.02 M Trizma buffer to drop from 8.3 to 6.3 per min at 0°C. (One W-A unit is essentially equivalent to one Roughton-Booth unit.) Pathway C-MYB transcription factor network, organism-specific biosystem (from Pathway Interaction Database) Erythrocytes take up carbon dioxide and release oxygen, organism-specific biosystem (from REACTOME) Erythrocytes take up oxygen and release carbon dioxide, organism-specific biosystem (from REACTOME) Metabolism, organism-specific biosystem (from REACTOME) Function Myocardial carbonic anhydrase 1/2 activation is significantly elevated in diabetic ischemic cardiomyopathy. may be involved in the pathogenesis of Abdominal aortic aneurysm The new prognostic biomarkers GRP78, Fructose-bisphosphate Aldolase A (ALDOA), Carbonic Anhydrase I (CA1) and Peptidyl-prolyl cis-trans isomerase A or Cyclophilin A (PPIA)) provided good survival prediction for TNM stage I-IV patients. A significant correlation was found between positive carbonic anhydrase I staining and oral squamous cell carcinoma for more advanced clinical stage and larger tumor size, but not for positive lymph node metastasis, distal metastasis, and recurrence. Synonyms Carbonic Anhydrase I; carbonate dehydRatase; carbonic anhydrase; anhydrase; carbonate anhydrase; carbonic acid anhydrase; carboxyanhydrase; carbonic anhydrase A; carbonate hydro-lyase; EC 4.2.1.1; 9001-03-0; CA-I; CA1 category Specialty Chemicals(c26) cas_num 9001-03-0 Basic Info-
Product Name:
Carbonic anhydrase
Other Name:Carbonic anhydrase;Dehydratase,carbonate;E.C. 4.2.1.1;Anhydrase;Carbonate anhydrase;Carbonate dehydratase;EC 4.2.1.1;Carbonic acid anhydrase;Carboxyanhydrase;Carbonate anhydrases;Carbonic anhydrases;Preprocarbonic anhydrase;Procarbonic anhydrase;Novozyme NS 81239;Carbonic acid anhydrases;Carbonate dehydratases;Anhydrases;Carboxyanhydrases;9044-52-4;9052-41-9;130303-03-6;130303-05-8
CAS No.:9001-03-0
InChIKeys:IRXYDYDYZGPTNB-UHFFFAOYSA-N
Molecular Weight:397.751
Exact Mass:396.079
HScode:35079090
Categories:
Characteristics-
PSA:
157
Water Solubility:Soluble in water
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History4 Inquiries
Country Product Purchase Quantity Date Posted 
France
Carbonic Anhydrase
1 KG Nov 30, 2023
France
Carbonic Anhydrase
1 KG Jul 30, 2025
France
Carbonic anhydrase
100 KG Sep 29, 2025 
Turkey
Carbonic anhydrase manufacturer
500 KG Oct 31, 2023 Post an enquiry for this product