Native Bovine Protein Disulfide Isomerase
37318-49-3
95%
Yes
2026-11-12
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Native Bovine Protein Disulfide Isomerase Cat No NATE-0533 Description Protein Disulfide Isomerase (PDI) has the C-terminal ER retention sequence Lys-Asp-Glu-Leu. It has active, intracellular traffic to different cell compartments. PDI supports internalization of Chlamydia, cholera and diphtheria toxins in some hosts. PDI is required for Sindbis virus infection and aids in reducing HIV gp120 protein thiols. PDI facilitates formation of the correct disulfide bonds by promoting rapid reshuffling of disulfide pairings Abbr PDI, Native (Bovine) Alias PDI Source Bovine liver Species Bovine Applications Protein Disulfide Isomerase (PDI) is a ubiquitous, highly conserved redox chaperone enzyme from the thioredoxin superfamily. It is mainly l ocated in the ER, where it assists in protein-folding and thiol-disulfide exchanges. It is used to study functional role of PDI in parasite infection and the interaction between macrophage PDI and L. chagasi. Product Overview Protein Disulfide Isomerase (PDI) from bovine liver is a homodimer with a molecular weight of 107 kDa (gel filtration) and the molecular weight of the monomer has been reported at 57 kDA (SDS-PAGE). The enzyme is a glycoprotein with 12% total carbohydrate content, composed of 4.6% mannose, 2.5% galactose, 1.4% NANA, and 3.5% 2-acetamido-2-deoxyglucose. Form Lyophilized powder containing potassium phosphate buffer salts and stabilizer. Enzyme Commission Number EC 5.3.4.1 Activity 100-400 units/mg protein CAS No 37318-49-3 Purity >95% (SDS-PAGE) Unit Definition One unit cause a change in A650 of 0.01 per min of a 1.0 mg/mL solution of insulin in the presence of dithiothreitol at pH 7.5 at 25°C. Storage −20°C Synonyms Protein disulfide isomerase; PDI; EC 5.3.4.1; 37318-49-3; S-S rearrangase category Specialty Chemicals(c26) cas_num 37318-49-3 Basic Info-
Product Name:
EC 5.3.4.1
Other Name:DSBA;EC 5.3.4.1;CONNECTASH(TM) PROTEIN DISULFIDE-ISOMERASE;PROTEIN DISULFIDE ISOMERASE;PDI;THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA;Protein disulfide Isomerase bovine liver;protein disulfide isomerase from E. coli
CAS No.:37318-49-3
Molecular Formula:C7H5Cl2NO5S
InChIKeys:DHUYKLYJBKXDBM-UHFFFAOYSA-N
Molecular Weight:286.0893
Exact Mass:284.927
DSSTox ID:DTXSID00652245
Categories:
Characteristics-
PSA:
115
XLogP3:-1
Appearance:lyophilized powder
Density:1.775g/cm3
Boiling Point:496.2ºC at 760 mmHg
Flash Point:253.9ºC
Refractive Index:1.623
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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