Edoxaban
1 Inquiries
480449-70-5
0.98%
2026-07-02
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Edoxaban Cat No CEI-1319 Description Edoxaban is a novel inhibitor of factor Xa with Ki value of 0.56 nM. Product Overview Edoxaban is an oral factor Xa (FXa) inhibitor in clinical development for stroke prevention in patients with atrial fibrillation, an elderly population that frequently receives aspirin (ASA) and/or nonsteroidal anti-inflammatory drugs for concurrent illnesses. CAS No 480449-70-5 Molecular Weight 548.06 Purity 0.98 Storage Store at -20°C Synonyms DU-176 Targets factor Xa IC50 0.56 nM (Ki) Molecular Formula C24H30ClN7O4S Chemical Name N-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl-6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide Solubility 25°C: DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Other Chemical Drugs(c1420) cas_num 480449-70-5 Basic Info-
Product Name:
Edoxaban
Other Name:Ethanediamide,N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-;Ethanediamide,N-(5-chloro-2-pyridinyl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]-;N1-(5-Chloro-2-pyridinyl)-N2-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide;Edoxaban;DU 176;N-(5-Chloropyridin-2-yl)-N′-[(1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-[[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino]cyclohexyl]ethanediamide;876652-15-2
CAS No.:480449-70-5
Molecular Formula:C24H30ClN7O4S
InChIKeys:InChIKey=HGVDHZBSSITLCT-JLJPHGGASA-N
Molecular Weight:548.065
Exact Mass:548.06
EC Number:1592732-453-0
UNII:NDU3J18APO
DSSTox ID:DTXSID50197398
NCI Thesaurus Code:C96539
Color/Form:White to pale yellowish-white crystalline powder
ATC Code:B01|B01AF03|B - Blood and blood forming organs
HScode:2934999090
Categories:
Characteristics-
PSA:
165
XLogP3:1.4
Density:1.4±0.1 g/cm3
Melting Point:Crystals as monohydrate from ethanol + water. MP: 245-48 (decomposes) /Edoxaban tosylate/
Refractive Index:1.646
Water Solubility:In water, 93.29 mg/L at 25 °C (est)
Storage Conditions:Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 °C. /Edoxaban tosylate/|Store at 20-25 °C (68-77 °F); excursions permitted to 15 deg - 30 °C (59 deg - 86 °F). /Edoxaban tosylate/
Vapor Pressure:2.03X10-21 mm Hg at 25 °C (est)
PKA:6.7None
Henrys Law Constant:Henry's Law constant = 3.11X10-34 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKa 6.7 /Edoxaban tosylate/
Experimental Properties:The solublilty decreases with increasing pH. It is slightly soluble in water, pH 3 to 5 buffer, very slightly soluble at pH 6 to 7; practically insoluble at pH 8 to 9 /Edoxaban tosylate/|Hydroxyl radical reaction rate constant = 1.55X10-12 cu cm/molec-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
China
Edoxaban TBSYLATE MONOHYDRATE 99% white powder
1 MT Jul 4, 2023 Post an enquiry for this product