Native Guinea pig Transglutaminase
3 Inquiries
80146-85-6
2026-09-29
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Native Guinea pig Transglutaminase Cat No NATE-0715 Description Transglutaminase from guinea pig liver consists of a single polypeptide chain of 691 amino acid residues. It has six potential glycosylation sites (Asn-X-Ser or Asn-X-Thr), but it is not glycosylated. The molecular mass is approximately 76.6 kDa. It is calcium dependent and has several calcium binding sites. The enzyme is inhibited by iodoacetamide and N-ethylmaleimide in the presence of calcium. It catalyzes the incorporation of small molecular weight amines into γ-glutamine sites of proteins. In the absence of small molecular weight amines, it catalyzes the cross linking of proteins that results in the formation of γ-glutamyl-ε-lysine side chain peptides. Liver transglutaminase is a nonzymogenic enzyme. Abbr Transglutaminase, Native (Guinea pig) Alias Factor XIIIa Source Guinea pig liver Species Guinea pig Applications This product from Creative Enzymes has been used to demonstrate that tissue transglutaminase (tTG) selectively deamidates gluten peptides, which results in strongly enhanced T cell-stimulatory activity. It has also been used to assess immune responses to A-gliadin peptides. Furthermore, it has been used to demonstrate that tTG selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Transglutaminase has been used in a study to improve quantifiable assays to fully characterize the role of transglutaminase in diseases such as Huntington′s disease and Alzheimer′s disease.Transglutaminase has also been used in a study to develop a nonradioactive dot blot assay for transglutaminase activity. Form Lyophilized powder containing Tris and dithioerythritol Enzyme Commission Number EC 2.3.2.13 Activity > 1.5 units/mg protein CAS No 80146-85-6 Unit Definition One unit will catalyze the formation of 1.0 μmole of hydroxamate per min from Nα-Z-Gln-Gly and hydroxylamine at pH 6.0 at 37°C. (L-Glutamic acid γ-monohydroxamate is the standard.) Storage −20°C Buffer H2O: soluble 1.0 mg/mL, clear Synonyms transglutaminase; EC 2.3.2.13; 80146-85-6; transglutaminase; Factor XIIIa; fibrinoligase; fibrin stabilizing factor; glutaminylpeptide γ-glutamyltransferase; polyamine transglutaminase; tissue transglutaminase; R-glutaminyl-peptide:amine γ-glutamyl transferase; protein-glutamine γ-glutamyltransferase category Amino Acids and Derivatives(c1517) cas_num 80146-85-6 Research & Reference NoteNative Guinea pig Transglutaminase is listed on ECHEMI for industrial / laboratory sourcing. This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Authoritative sourcesDisclaimer: This listing is for industrial and laboratory research use. Product information on ECHEMI is provided for sourcing and specification reference. It is not medical advice, a clinical recommendation, or an approved therapy description. Always verify regulatory status, purity, and intended use with the supplier and applicable authorities before purchase or use.
Reviewed by ECHEMI Scientific Review - Platform editorial review for research chemicals
Basic Info-
Product Name:
Glutaminylpeptide γ-glutamyltransferase
Other Name:Glutaminylpeptide γ-glutamyltransferase;Glutamyltransferase,glutaminylpeptide γ-;E.C. 2.3.2.13;Transglutaminase;Polyamine transglutaminase;PPQ 6117;Activa TG;Akuthiba TG-S;Activa WM;Activa TG-S;Activa TG-M;Activa TG-K;Activa TG-TI;Activa MP;Activa Supercurd;Koshikeep;Activa;Activa STG-M Koshikeep;Activa Koshikeep;Activa TGB;Activa TG-H;Activa YG;Activa TG-HP;Activa G-S;Activa TG-AK;Microbial transglutaminase;MTGase;Activa RM;Activa TG-RM;Activa TG-FP;Activa STG Koshikeep;TG-AK;Activa KS-CT;Transglutaminase (TG);TG (enzyme);Biobond TG-SC;Biobond TG-SC,TG-TU transglutaminase;Activa TI;Moo Gloo TI;KS-CT;Activa STG-M;Activa STG;Activa Koshi Keep STG-M;300711-04-0
CAS No.:80146-85-6
Categories:
Characteristics-
Appearance:
lyophilized powder
Water Solubility:H2O: soluble1.0mg/mL, clear
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
Respiratory sensitization, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P342+P316 If experiencing respiratory symptoms: Get emergency medical help immediately.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History3 Inquiries
Country Product Purchase Quantity Date Posted 
Italy
Food Grade High Quality Transglutaminase powder / Glutamine transaminase with Best Price 80146-85-6
1 KG Oct 27, 2023
Italy
Food Grade High Quality Transglutaminase powder / Glutamine transaminase with Best Price 80146-85-6
1 KG Oct 27, 2023 
India
transglutanimase
100 KG Oct 12, 2023 Post an enquiry for this product