Native Escherichia coli Asparaginase
2 Inquiries
9015-68-3
Yes
2026-11-15
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Native Escherichia coli Asparaginase Cat No PHAM-226 Description Asparaginase (EC 3.5.1.1, USAN) or Colaspase (BAN) is an enzyme that catalyzes the hydrolysis of asparagine to aspartic acid. Asparaginases are enzymes expressed and produced by microorganisms. Abbr Asparaginase (E. coli) Source Escherichia coli Applications Asparaginase is used in enzymatic assays and to convert asparagine to aspartic acid. Asparaginase is used to reduce the formation of acrylamide in starchy food products. It is also used as a chemotherapy agent for acute lymphoblastic leukemia. Product is from Escherichia coli and is provided as a lyophilized powder containing sodium chloride. Form lyophilized powder Enzyme Commission Number EC 3.5.1.1 CAS No 9015-68-3 Composition Protein, > 60% Unit Definition One unit will liberate 1.0 μmole of ammonia from L-asparagine per min at pH 8.6 at 37 °C. Storage 2-8°C Synonyms EC 3.5.1.1; Asparaginase; Colaspase; L-asparaginase; L-asparagine amidohydrolase category Enzymes and Coenzymes Drugs(c1513) cas_num 9015-68-3 ECHEMI Editorial ReferenceL-Asparaginase (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1].
Asparaginate is an alpha-amino-acid anion that is the conjugate base of asparagine, arising from deprotonation of the carboxy group. It is a conjugate base of an asparagine.|Asparaginase is a bacterial enzyme that is used as an antineoplastic agent, largely in the therapy of acute lymphocytic leukemia. L-asparaginase has many side effects, one of which is hepatic injury that is characterized by inhibition of hepatic protein synthesis and steatosis, which can be severe and lead to death from hepatic failure.|A hydrolase enzyme that converts L-asparagine and water to L-aspartate and NH3. EC 3.5.1.1.Basic Info-
Product Name:
Asparaginase
Other Name:Asparaginase;E.C. 3.5.1.1;NSC 109229;L-Asparaginase;EC 3.5.1.1;L-Asparagine amidohydrolase;Elspar;Leunase;Crasnitin;α-Asparaginase;MK 965;L-Asnase;Kidrolase;Colaspase;Oncospar;Acrylaway L;Preventase M;Asparaginase medac;PreventASe;Asparaginases;Asparaginase 2;α-Asparaginases;L-Asparagine amidohydrolases;L-Asparaginases;Kidrolases;Crasnitins;Leunases;Spectrila;9037-33-6;9037-34-7;9060-77-9
CAS No.:9015-68-3
InChIKeys:DCXYFEDJOCDNAF-UHFFFAOYSA-M
Molecular Weight:295.35
Exact Mass:151.009186
EC Number:232-765-3
DSSTox ID:DTXSID3042554
ATC Code:L01XX02|L - Antineoplastic and immunomodulating agents
Categories:
Characteristics-
PSA:
0.00000
XLogP3:1.78
Appearance:suspension
Density:1.4±0.1 g/cm3
Boiling Point:204.5±23.0 °C at 760 mmHg
Flash Point:77.5±22.6 °C
Refractive Index:1.745
Storage Conditions:2-8°C
Toxicity:Peritoneal-rat LD50: 8204 mg/kg; subcutaneous-rat LD50; 7568 mg/kg
Flammability characteristics:Flammable; burning produces irritating fumes
Specific rotation:D20 -30 to -32°
Hazard IdentificationClassification of the substance or mixture
Skin sensitization, Category 1
Reproductive toxicity, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H317 May cause an allergic skin reaction
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P333+P317 If skin irritation or rash occurs: Get medical help.
P321 Specific treatment (see ... on this label).
P362+P364 Take off contaminated clothing and wash it before reuse.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15 days
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted 
Pakistan
ASPARAGINASE
1 KG Jul 11, 2025 
Russia
High Quality Asparaginase CAS NO.9015-68-3
2 KG Apr 24, 2025 Post an enquiry for this product
