Indirubin
479-41-4
99%
2026-08-14
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Indirubin Cat No CEI-0096 Description Indirubin CAS No 479-41-4 Molecular Weight 262.26 Purity >99% Storage 2 years at -20 centigrade Targets CDK Molecular Formula C16H10N2O2 Solubility No In vitro Indirubin, a bis-indole obtained from various natural sources, is responsible for the reported antileukemia activity of a Chinese Medicinal recipe, Danggui Longhui Wan.A dramatic cytostatic effect, as measured by actual cell counts and associated with a sharp G1 phase arrest, is induced by 1-methyl-indirubins, a subfamily of AhR-active but kinase-inactive indirubins.In the time-course experiment, CYP1A1 mRNA is induced by indirubin transiently. Indirubin was also metabolized by CYP1A1 and lost its ligand activity. Indirubin would appear to be a good substrate of CYP1A1 given its low dissociation constant.Levels of cytochrome P450 1A1/2 proteins and mRNAs in the liver of mice dosed with indirubin were also enhanced. category Antineoplastic Agents(c1417) cas_num 479-41-4 Basic Info-
Product Name:
Indirubin
Other Name:2H-Indol-2-one,3-(1,3-dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-;[Δ2,3′-Biindoline]-2′,3-dione;Indirubin;3-(1,3-Dihydro-3-oxo-2H-indol-2-ylidene)-1,3-dihydro-2H-indol-2-one;C.I. 73200;Indigopurpurin;Indigo red;Couroupitine B;NSC 105327;53570-83-5;396106-96-0;1199246-06-4
CAS No.:479-41-4
Molecular Formula:C16H10N2O2
InChIKeys:InChIKey=CRDNMYFJWFXOCH-UHFFFAOYSA-N
Molecular Weight:262.26
Exact Mass:262.26
EC Number:1806241-263-5
UNII:1LXW6D3W2Z|V86L8P74GI
NSC Number:105327
HScode:2933990090
Categories:
Characteristics-
PSA:
65.4
XLogP3:2.93420
Appearance:Reddish-violet powder
Density:1.4±0.1 g/cm3
Melting Point:204-205 °C
Boiling Point:496.6°C at 760 mmHg
Flash Point:207.0±28.9 °C
Refractive Index:1.709
Vapor Pressure:5.34E-10mmHg at 25°C
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product