IC-87114
371242-69-2
99%
2026-07-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Description
ProductName IC-87114 Cat No CEI-0141 Description IC-87114 can inhibit PI3K-delta with IC50 of 500 nM. CAS No 371242-69-2 Molecular Weight 397.43 Purity >99% Storage 2 years at -20centigrade Powder Targets PI3K-delta Molecular Formula C22H19N7O Chemical Name 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)-one Solubility DMSO 0.66 mg/mL Water In vitro IC87114 is a selective PI3K-delta selectivity relative to the other class I PI3Ks. The IC50 of IC87114 for PI3K-delta inhibition was 0.5 uM whereas the IC50 values for PI3K-alpha, PI3K-beta, and PI3K-gamma were 100 uM, 75 uM, and 29 uM, respectively. IC87114 is 58-fold more selective for PI3K-delta relative to PI3K-gamma, and over 100-fold selective relative to PI3K-alpha and PI3K-beta. category Inhibitors(c1514) cas_num 371242-69-2 Basic Info-
Product Name:
IC 87114
Other Name:4(3H)-Quinazolinone,2-[(6-amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-;2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;IC 87114;2-[(6-Aminopurin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one
CAS No.:371242-69-2
Molecular Formula:C22H19N7O
InChIKeys:InChIKey=GNWHRHGTIBRNSM-UHFFFAOYSA-N
Molecular Weight:397.43
Exact Mass:397.43
UNII:9HC746B1KF
DSSTox ID:DTXSID00190617
Categories:
Characteristics-
PSA:
102
XLogP3:2.61
Density:1.4±0.1 g/cm3
Boiling Point:673.7±65.0 °C at 760 mmHg
Flash Point:361.2±34.3 °C
Refractive Index:1.759
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product