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PAC-1

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CAS No.:

315183-21-2

Content:

99%

Price valid (until):

2026-08-12

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Creative Enzymes

Company Type:

Manufactory

Location:

United States

Qualification:

Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Product Description
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Description

ProductName	PAC-1
Cat No	CEI-0186
Description	PAC-1
CAS No	315183-21-2
Molecular Weight	392.49
Purity	>99%
Storage	2 years at -20 centigrade
Targets	procaspase-3
Molecular Formula	C23H28N4O2
Solubility	No
In vitro	PAC-1 activates procaspase-3 by chelating zinc ions, thus relieving the zinc-mediated inhibition and allowing procaspase-3 to auto-activate itself to caspase-3.PAC-1 can not induce cell death and caspase-3 activation in Apaf-1 knockout cells, suggesting that apoptosome formation is essential for caspase-3 activation by PAC-1-mediated cell death.
category	Inhibitors(c1514)
cas_num	315183-21-2

Basic Info

Product Name:

Procaspase activating compound 1

Other Name:

1-Piperazineacetic acid,4-(phenylmethyl)-,2-[[2-hydroxy-3-(2-propen-1-yl)phenyl]methylene]hydrazide;1-Piperazineacetic acid,4-(phenylmethyl)-,[[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazide;Procaspase activating compound 1;PAC 1

CAS No.:

315183-21-2

Molecular Formula:

C23H28N4O2

InChIKeys:

InChIKey=YQNRVGJCPCNMKT-UHFFFAOYSA-N

Molecular Weight:

392.5

Exact Mass:

392.49

UNII:

9LIS8N0B2C

NSC Number:

743444

HScode:

29335990

Categories:

Inhibitors

Characteristics

PSA:

68.17000

XLogP3:

2.65530

Appearance:

white

Density:

1.1±0.1 g/cm3

Refractive Index:

1.597

Water Solubility:

DMSO: ≥10mg/mL

Storage Conditions:

Store at +4°C

See More Procaspase activating compound 1 Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation H400 Very toxic to aquatic life
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Procaspase activating compound 1 Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.
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PAC-1

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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