Crenolanib(CP-868596)
670220-88-9
99%
2026-08-20
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Crenolanib(CP-868596) Cat No CEI-0058 Description Crenolanib(CP-868596) can inhibit PDGFR-alpha with IC50 of 10 nM. CAS No 670220-88-9 Molecular Weight 443.54 Purity >99% Storage 2 years at -20centigrade Powder Targets PDGFR-alpha Molecular Formula C26H29N5O2 Chemical Name 1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine Solubility DMSO 89 mg/mL Water In vitro The CP-868,596 is a potent, oral, selective inhibitor of PDGFR-beta tyrosine kinase, with an IC 50 of 0.4 ng/ml while PDGFR-beta is commonly overexpressed in the stroma and pericytes of several solid organ tumour types. CP-868,596 is greater than 100-fold more selective for PDGFR than for other kinases, such as c-KIT, VEGFR-2, TIE-2, FGFR-2, EGFR, erbB2, and Src. category Antineoplastics(c1126) cas_num 670220-88-9 Basic Info-
Product Name:
Crenolanib
Other Name:4-Piperidinamine,1-[2-[5-[(3-methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-;1-[2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine;[1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine;ARO 002;Crenolanib;CP 868596;1-[2-[5-[(3-Methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine;866109-23-1
CAS No.:670220-88-9
Molecular Formula:C26H29N5O2
InChIKeys:InChIKey=DYNHJHQFHQTFTP-UHFFFAOYSA-N
Molecular Weight:443.54076
Exact Mass:443.54
Categories:
Characteristics-
PSA:
78.4
XLogP3:3.7
Density:1.4±0.1 g/cm3
Flash Point:363.0±34.3 °C
Refractive Index:1.704
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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