Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Product Description
-
Seller Information
-
Description
ProductName TAME Cat No CEI-0278 Description Tosyl-L-Arginine Methyl Ester (TAME) is an APC inhibitor. CAS No 901-47-3 Molecular Weight 342.41 Purity >99% Storage 2 years at -20 centigrade Targets APC Molecular Formula C14H22N4O4S Chemical Name (S)-methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate Solubility DSMO 69 mg/mL Water 69 mg/mL Ethanol 3 mg/mL In vitro TAME inhibits cyclin proteolysis in mitotic Xenopus egg extract with IC50 of 12 uM. TAME at concentration of 1-200 uM arrests interphase extract treated with recombinant cyclin B1/Cdc2 complex in mitosis, with stable cyclin B1 and phosphorylated Cdc27. TAME accelerates the ATP hydrolysis process about 12-fold. TAME interacts with beta and gamma phosphate and the adenine ring of ATP by the guanidinium group and the aromatic ring. category Amino Acids and Derivatives(c1517) cas_num 901-47-3 Basic Info-
Product Name:
α-Tosyl-L-arginine methyl ester
Other Name:L-Arginine,N2-[(4-methylphenyl)sulfonyl]-,methyl ester;Arginine,N2-(p-tolylsulfonyl)-,methyl ester,L-;Arginine,(p-tolylsulfonyl)-,methyl ester;TAME (pharmaceutical);α-N-p-Toluenesulfonyl-L-arginine methyl ester;Methyl p-toluenesulfonyl-L-argininate;Methyl Nα-p-toluenesulfonyl-L-argininate;α-Tosyl-L-arginine methyl ester;p-Toluenesulfonyl-L-arginine methyl ester;p-Tolylsulfonyl-L-arginine methyl ester;N1-Tosyl-L-arginine methyl ester;p-Tosyl-L-arginine methyl ester;N-α-Toluenesulfonyl-L-arginine methyl ester;α-N-p-Tosyl-L-arginine methyl ester;TAME;(S)-Methyl 5-guanidino-2-(4-methylphenylsulfonamido)pentanoate;2706-74-3
CAS No.:901-47-3
Molecular Formula:C14H22N4O4S
InChIKeys:InChIKey=FKMJXALNHKIDOD-LBPRGKRZSA-N
Molecular Weight:342.414
Exact Mass:342.41
UNII:1H7BKF44U1
Categories:
Characteristics-
PSA:
142.75000
XLogP3:0.77
Density:1.3±0.1 g/cm3
Melting Point:-80°C
Boiling Point:516.5±60.0 °C at 760 mmHg
Flash Point:266.1±32.9 °C
Refractive Index:1.591
Vapor Density:Relative vapour density (air = 1): 3.6
Explosive limit:Explosive limits , vol% in air: 1.1-7.1
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
-
Location:
Shirley, New York 11967, USA
-
Payment Terms:
TT against copy of documents,D/P
-
Average lead Time:
15
-
Total Annual Revenue:
$1 million-$2.5 million
-
Year of Establishment:
2004
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product