BMS-265246
582315-72-8
99%
2026-06-27
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName BMS-265246 Cat No CEI-0283 Description BMS-265246 CAS No 582315-72-8 Molecular Weight 345.34 Purity >99% Storage 2 years at -20centigrade Powder Targets CDK1/cyclin B, CDK2/cyclin E Molecular Formula C18H17F2N3O2 Chemical Name (4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-(2, 6-difluoro-4-methylphenyl)methanone Solubility DMSO 20 mg/mL, Water In vitro BMS265246 can potently inhibit CDK1/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM. BMS265246 which binds to CDK2 shows the inhibitor resides coincident with the ATP purine binding site and forms important H-bonds with Leu83 on the protein backbone. BMS265246 exhibits CDK1 and CDK2 potency that is 25- and 11-fold more potent versus CDK1 and CDK2, respectively. category Inhibitors(c1514) cas_num 582315-72-8 Basic Info-
Product Name:
BMS-265246
Other Name:BMS-265246;(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-methanone;(4-Butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)-methanoneBMS265246;BMS-265246, >=98%
CAS No.:582315-72-8
Molecular Formula:C18H16F2N3O2
InChIKeys:SCFMWQIQBVZOQR-UHFFFAOYSA-N
Molecular Weight:344.3353464
Exact Mass:345.129
Categories:
Characteristics-
PSA:
67.9
XLogP3:3.9
Density:1.304±0.06 g/cm3(Predicted)
Boiling Point:552.9±50.0°C at 15 mmHg
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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