Lomustine
13010-47-4
99%
2026-08-14
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Lomustine Cat No CEI-0366 Description By damaging the DNA, lomustine inhibits cancer cells and stops cells from dividing. Lomustine inhibits the growth of ZR-75-1 and U373 with IC50 of 12 uM and 15 uM, respectively. Lomustine reduces the level of expression of the DNA repair protein O6-alkylguanine-DNA alkyltransferase. Alias CeeNU CAS No 13010-47-4 Molecular Weight 233.7 Purity >99% Storage 2 years at -20 centigrade Synonyms CeeNU Targets AGT Molecular Formula C9H16ClN3O2 Solubility DMSO 47 mg/mL, Water category Antineoplastic Agents(c1417) cas_num 13010-47-4 Basic Info-
Product Name:
Lomustine
Other Name:Urea,N-(2-chloroethyl)-N′-cyclohexyl-N-nitroso-;Urea,1-(2-chloroethyl)-3-cyclohexyl-1-nitroso-;N-(2-Chloroethyl)-N′-cyclohexyl-N-nitrosourea;3-Cyclohexyl-1-(2-chloroethyl)-1-nitrosourea;CCNU;1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea;Lomustine;NSC 79037;1-(2-Chloroethyl)-3-cyclohexylnitrosourea;ICIG 1109;Belustine;1-(2-Chloroethyl)-1-nitroso-3-cyclohexylurea;Lomustin;CeeNU;CiNu;Chloroethylcyclohexylnitrosourea;SRI 2200;Cecenu;NCI C04740;RB 1509;Lustine;Moostine;Lomtin
CAS No.:13010-47-4
Molecular Formula:C9H16ClN3O2
InChIKeys:InChIKey=GQYIWUVLTXOXAJ-UHFFFAOYSA-N
Molecular Weight:233.7
Exact Mass:233.70
EC Number:235-859-2
UNII:7BRF0Z81KG
NSC Number:759635|79037
DSSTox ID:DTXSID2023222
NCI Thesaurus Code:C617
Color/Form:Solid|Yellow powder
ATC Code:L - Antineoplastic and immunomodulating agents
HScode:29299090
Categories:
Characteristics-
PSA:
61.8
XLogP3:2.8
Appearance:Solid
Density:1.3840 (rough estimate)
Melting Point:89 °C (approx)
Boiling Point:63.6°C (rough estimate)
Refractive Index:1.5790 (estimate)
Water Solubility:7.55e-01 g/L
Storage Conditions:−20°C
Vapor Pressure:1.01X10-5 mm Hg at 25 deg C (est)
Toxicity:Oral-Rat LD50: 70 mg/kg; Oral-Mouse LD50:38 mg/kg
Flammability characteristics:Flammable; decomposes toxic chloride and nitrogen oxide gas in the fire
Henrys Law Constant:Henry's Law constant = 1.9X10-10 atm-cu m/mole at 25 °C (est)
Experimental Properties:Hydroxyl radical reaction rate constant = 2.2X10-11 cu cm/molecule-sec at 25 °C (est)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Carcinogenicity, Category 1B
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H350 May cause cancer
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P318 IF exposed or concerned, get medical advice.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20 deg C. Light sensitive.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
