β-Lapachone
4707-32-8
98%
2026-08-17
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName β-Lapachone Cat No CEI-0468 Description Cell-permeable. A DNA topoisomerase I inhibitor. Unlike Camptothecin, β-lapachone does not stabilize the cleavable complex, indicating a novel mode of action. Induces apoptosis in HL-60 and human prostate cancer cells via a p53-independent mechanism and blocks the cell cycle at G0/G1. Also acts as a histone demethylase inhibitor selective to JMJ2DE (IC50 =3.6 µM). Appearance White solid Product Overview A DNA topoisomerase I inhibitor and a histone demethylase (HDM) inhibitor CAS No 4707-32-8 Molecular Weight 435.52 Purity >98% by TLC Storage -20 centigrade Targets TOP1MT Molecular Formula C15H14O3 Chemical Name 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione Solubility DMSO (~ 25 mg/ml) Shipping Conditions Gel pack category Inhibitors(c1514) cas_num 4707-32-8 Basic Info-
Product Name:
β-Lapachone
Other Name:2H-Naphtho[1,2-b]pyran-5,6-dione,3,4-dihydro-2,2-dimethyl-;3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione;β-Lapachone;SL 11001;NSC 26326;NSC 629749;ARQ 501;MB 12066;2,2-Dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione
CAS No.:4707-32-8
Molecular Formula:C15H14O3
InChIKeys:InChIKey=QZPQTZZNNJUOLS-UHFFFAOYSA-N
Molecular Weight:242.27
Exact Mass:242.27
UNII:6N4FA2QQ6A
NSC Number:629749|26326
DSSTox ID:DTXSID90197019
NCI Thesaurus Code:C28694
HScode:2914399090
Categories:
Characteristics-
PSA:
43.4
XLogP3:2.2
Density:1.3±0.1 g/cm3
Melting Point:124.5-125.5 °C
Boiling Point:381.4ºC at 760 mmHg
Flash Point:169.7±27.9 °C
Refractive Index:1.595
Storage Conditions:-20°C Freezer
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product