Chidamide
743420-02-2
95%
2026-07-19
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Chidamide Cat No CEI-0504 Description Cell-permeable. A new benzamide class of histone deacetylase (HDAC) inhibitor with marked anti-tumor activity. It increases histone H3 acetylation levels in LoVo and HT29 colon cancer cells at concentrations as low as 4 µM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. Appearance White solid Product Overview A potent histone deacetylase inhibitor CAS No 743420-02-2 Molecular Weight 382.45 Purity >95% by HPLC Storage -20 centigrade Targets HDAC Molecular Formula C22H19FN4O2 Chemical Name N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide Solubility DMSO (200 mM) Shipping Conditions Gel pack category Specialty Chemicals(c26) cas_num 743420-02-2 Basic Info-
Product Name:
N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide
Other Name:Benzamide,N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-;Benzamide,N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]-;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide
CAS No.:743420-02-2
Molecular Formula:C22H19FN4O2
InChIKeys:InChIKey=WXHHICFWKXDFOW-UHFFFAOYSA-N
Molecular Weight:390.4102632
Exact Mass:390.41
Categories:
Characteristics-
PSA:
97.1
XLogP3:2.3
Density:1.3±0.1 g/cm3
Flash Point:316.8±31.5 °C
Refractive Index:1.691
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product