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N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide structure

CAS No:
743420-02-2
Formula:
C22H19FN4O2
Chemical Name:
N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide
Synonyms:
Benzamide,N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-;Benzamide,N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propenyl]amino]methyl]-;N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

Description

Chidamide is a synthetic benzamide-type HDAC inhibitor, inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 95, 160, 67 and 78 nM, respectively.

N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide Basic Attributes

Molecular Weight：

390.4102632

Exact Mass：

390.41

Characteristics

PSA：

97.1

XLogP3：

2.3

Density：

1.3±0.1 g/cm3

Flash Point：

316.8±31.5 °C

Refractive Index：

1.691

Drug Function and Efficacy

Not described in detail

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Chidamide
Manufacturer	Shenzhen Weixin Pharmaceutical Co., Ltd.

Chidamide Tablets
Ingredients	Chidamide.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	5mg
Manufacturer	Shenzhen Weixin Pharmaceutical Co., Ltd.

Registered Holders

Shenzhen Weixin Pharmaceutical Co., Ltd.

China
Active
Jiangsu Purun Biopharmaceutical Co., Ltd.

China
Inactive

Recommended Suppliers of N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

Creative Enzymes Contact Supplier

US
6 YRS

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Manufactory Supplier of Coenzymes,Inhibito,Enzymes,Zymogens,Substrates

Chidamide

CAS No.: 743420-02-2

Content: 95%

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Guide of N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

Description
Basic Attributes
Characteristics
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers

N-(2-Amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]benzamide

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