Fosamprenavir Calcium Salt
1 Inquiries
226700-81-8
0.98%
2026-08-10
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Inquiry History
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Description
ProductName Fosamprenavir Calcium Salt Cat No CEI-1340 Product Overview GW433908G is a selective inhibitor of antiretroviral protease with the concentration of 1395 mg nM once daily in clinical trial. Antiretroviral protease is a subfamily of protease inhibitors and plays a pivotal role in treating HIV/AIDS and HCV infection. It has been reported that drugs designed as protease inhibitors can prevent viral replication by selectively binding to viral proteases (e. g. HIV-1 protease) and blocking proteolytic cleavage of protein precursors that are necessary for the production of infectious viral particles. GW433908 is a potent antiretroviral protease inhibitor and has improved solubility than amprenavir capsules. Many clinical studies have been done to examine GE433908 safety and pharmacokinetic profiles. In healthy male volunteers, administered GW433908 as tablets or suspension, food had slight effect on its pharmacokinetics and with fewer tablets GW433908 were well tolerated and delivered plasma amprenavir concentrations equivalent to the recommended therapeutic amprenavir dose which may be of clinical benefit in the treatment of HIV infection. As a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, GW433908 (1395 mg, QD) combined with efavirenz (200 mg, QD) decreased plasma APV exposure when tested with healthy volunteers. CAS No 226700-81-8 Molecular Weight 623.67 Purity 0.98 Storage Store at -20°C Synonyms GW 433908G; Lexiva; GW433908G; GW-433908G Targets Protease Molecular Formula C25H34CaN3O9PS Chemical Name calcium; [(2R,3S)-1-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-[[(3S)-oxolan-3-yl]oxycarbonylamino]-4-phenylbutan-2-yl] phosphate Solubility Soluble in Water Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Synthetic Fragrances(c1911) cas_num 226700-81-8 Basic Info-
Product Name:
Fosamprenavir calcium
Other Name:Carbamic acid,N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-,(3S)-tetrahydro-3-furanyl ester,calcium salt (1:1);Carbamic acid,[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-,C-[(3S)-tetrahydro-3-furanyl] ester,calcium salt (1:1);GW 433908G;Fosamprenavir calcium;Lexiva;Telzir
CAS No.:226700-81-8
Molecular Formula:C25H36N3O9PS.Ca
InChIKeys:InChIKey=XOGQXKBFJZURRD-HQROKSDRSA-N
Molecular Weight:623.668921
Exact Mass:623.137939
EC Number:1806241-263-5
UNII:ID1GU2627N
DSSTox ID:DTXSID0046777
NCI Thesaurus Code:C61771
ATC Code:J05AE07
Categories:
Characteristics-
PSA:
192
XLogP3:5.44910
Melting Point:282-2840C
Storage Conditions:-20°C Freezer, Under Inert Atmosphere
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
United States
Fosamprenavir calcium
15 KG Sep 26, 2025 Post an enquiry for this product