Fosamprenavir calcium(226700-81-8)
1 Inquiries
226700-81-8
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99%
Ningbo
Eagle
25KG/drum
2029-11-30
Dimethyl sufoxide
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceGW433908 is a phosphate ester prodrug of the antiretroviral protease inhibitor amprenavir, with improved solubility over the parent molecule and a potential for reduced pill burden on current dosing regimens; GW433908G is the calcium salt of the prodrug.IC50 Value:Target: HIV Proteasein vitro: There were no significant changes in buprenorphine or PI plasma levels and no significant changes in medication adverse effects or opioid withdrawal. Increased concentrations of the inactive metabo
Fosamprenavir Calcium is the calcium salt form of fosamprenavir, prodrug of amprenavir, and a human immunodeficiency virus (HIV) protease inhibitor with antiviral property. Fosamprenavir is converted to amprenavir by cellular phosphatases in the epithelial cells of the intestine. Then amprenavir binds to the active site of HIV-1 protease, thereby preventing the proteolytic cleavage of viral Gag-Pol polypeptide into individual functional proteins, thereby leading to the formation of immature non-infectious viral particles.Basic Info-
Product Name:
Fosamprenavir calcium
Other Name:Carbamic acid,N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-,(3S)-tetrahydro-3-furanyl ester,calcium salt (1:1);Carbamic acid,[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-1-(phenylmethyl)-2-(phosphonooxy)propyl]-,C-[(3S)-tetrahydro-3-furanyl] ester,calcium salt (1:1);GW 433908G;Fosamprenavir calcium;Lexiva;Telzir
CAS No.:226700-81-8
Molecular Formula:C25H36N3O9PS.Ca
InChIKeys:InChIKey=XOGQXKBFJZURRD-HQROKSDRSA-N
Molecular Weight:623.668921
Exact Mass:623.137939
EC Number:1806241-263-5
UNII:ID1GU2627N
DSSTox ID:DTXSID0046777
NCI Thesaurus Code:C61771
ATC Code:J05AE07
Categories:
Characteristics-
PSA:
192
XLogP3:5.44910
Melting Point:282-2840C
Storage Conditions:-20°C Freezer, Under Inert Atmosphere
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H361 Suspected of damaging fertility or the unborn child
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Dimethyl sufoxide
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Location:
Lianqian East Road650, Siming district, Xiamen, China
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Payment Terms:
TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
5-10
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Year of Establishment:
2020
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Fosamprenavir calcium
15 KG Sep 26, 2025 Post an enquiry for this product