Vinorelbine Tartrate
125317-39-7
98%
2026-07-02
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Vinorelbine Tartrate Cat No CEI-0562 Description A semi-synthetic vinca alkaloid that displays potent anti-mitotic and anti-tumor properties. Its main mechanism of action is thought to be inhibition of microtubule dynamics, which results in mitotic arrest and eventual cell death. Acts as a microtubule destabilizing agent. At high concentrations, it stimulates microtubule depolymerization and mitotic spindle destruction. At lower clinically relevant concentrations, vinorelbine blocks mitotic progression. Its main targets are tubulin and microtubules. Unlike the taxanes, which bind poorly to soluble tubulin, vinorelbine can bind both soluble and microtubule-associated tubulin. Appearance White to off-white solid Product Overview An anti-mitotic and antitumor agent CAS No 125317-39-7 Molecular Weight 326.35 Purity >98% by HPLC Storage -20 centigrade Targets DNMTs Molecular Formula C₄₅H₅₄N₄O₈.C₈H₁₂O₁₂ Chemical Name 3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine [R-(R*,R*)-2-3-dihydroxybutanedioate (1:2)salt], 5′-Noranhydrovinoblastine tartrate, KW-2307, NVB, Navelbine tartrate Solubility DMSO (100 mM) Shipping Conditions Gel Pack category Antineoplastic Agents(c1417) cas_num 125317-39-7 Basic Info-
Product Name:
Navelbine
Other Name:Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-,methyl ester,(2β,3β,4β,5α,12R,19α)-,(2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt);C′-Norvincaleukoblastine,3′,4′-didehydro-4′-deoxy-,[R-(R*,R*)]-2,3-dihydroxybutanedioate (1:2) (salt);Vinorelbine ditartrate;KW 2307;Navelbine ditartrate;Vinorelbine tartrate;Navelbine;Nor-5′-anhydrovinblastine ditartrate;Aspidospermidine-3-carboxylic acid,4-(acetyloxy)-6,7-didehydro-15-[(2R,6R,8S)-4-ethyl-1,3,6,7,8,9-hexahydro-8-(methoxycarbonyl)-2,6-methano-2H-azecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-,methyl ester,(2β,3β,4β,5α,12β,19α)-,(2R,3R)-2,3-dihydroxybutanedioate (1:2) (salt);3′,4′-Didehydro-4′-deoxy-C′-norvincaleukoblastine tartrate;892125-21-2
CAS No.:125317-39-7
Molecular Formula:C45H54N4O8.2C4H6O6
InChIKeys:InChIKey=UUHYRRXICWUZHW-RPZOAHRESA-N
Molecular Weight:1079.11
Exact Mass:1078.427002
EC Number:1806241-263-5
DSSTox ID:DTXSID5047825
HScode:2942000000
Categories:
Characteristics-
PSA:
364
XLogP3:0.44920
Appearance:off-white powder
Density:1.36g/cm3
Melting Point:190 °C
Refractive Index:1.675
Water Solubility:H2O: 10 mg/mL
Storage Conditions:2-8°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Skin irritation, Category 2
Eye irritation, Category 2
Germ cell mutagenicity, Category 2
Reproductive toxicity, Category 1B
Specific target organ toxicity â repeated exposure, Category 1
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H341 Suspected of causing genetic defects
H360 May damage fertility or the unborn child
H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P203 Obtain, read and follow all safety instructions before use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P318 IF exposed or concerned, get medical advice.
P319 Get medical help if you feel unwell.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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