Lck inhibitor 2
944795-06-6
0.98%
2026-07-07
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName Lck inhibitor 2 Cat No CEI-1391 Product Overview Lck inhibitor 2 is a bis-anilinopyrimidine inhibitor of tyrosine kinases including LCK, BTK, LYN, SYK, and TXK. 27.The IC50 values are 13nM, 9nM, 3nM, 26nM and 2nM for Lck, Btk, Lyn, Btk and Txk respectively. Lck inhibitor 2 (Compound 9) inhibited 48 kinases with %control <1 (33 of them tyrosine kinases, almost half of the 71 tyrosine kinases in the panel). A further 27 kinases were bound with %control <10.Kd values for 16 kinases were determined and found to be below 100 nM. These included TXK (10 nM). CAS No 944795-06-6 Molecular Weight 335.36 Purity 0.98 Storage Store at -20°C Targets Tyrosine kinases IC50 13 nM(Lck) Molecular Formula C18H17N5O2 Chemical Name 3-[[4-(5-hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide Solubility Soluble in DMSO Shipping Conditions Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request category Specialty Chemicals(c26) cas_num 944795-06-6 Basic Info-
Product Name:
3-[[4-[(5-Hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]benzamide
Other Name:Benzamide,3-[[4-[(5-hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]-;3-[[4-[(5-Hydroxy-2-methylphenyl)amino]-2-pyrimidinyl]amino]benzamide;3-[[4-(5-Hydroxy-2-methylanilino)pyrimidin-2-yl]amino]benzamide
CAS No.:944795-06-6
Molecular Formula:C18H17N5O2
InChIKeys:InChIKey=SFCBIFOAGRZJNX-UHFFFAOYSA-N
Molecular Weight:335.35988
Exact Mass:335.36
Categories:
Characteristics-
PSA:
113
XLogP3:2.8
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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