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YM-155 hydrochloride

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CAS No.:

355406-09-6

Content:

0.98%

Sample Available:

Yes

Price valid (until):

2026-11-22

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Creative Enzymes

Company Type:

Manufactory

Location:

United States

Payment Terms:

TT against copy of documents,D/P

Average Lead Time:

15 days

Qualification:

Main Products:

Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

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Description

ProductName	YM-155 hydrochloride
Cat No	CEI-1590
Description	YM-155 hydrochloride is a potent and small-molecule inhibitor of survivin with IC50 value of 0.54 nM.
Product Overview	YM-155 hydrochloride is a novel small-molecule suppressant of surviving, the smallest member of inhibitor of apoptosis (IAP) gene family. It exhibits a potent suppressive activity against survivin but has little effect on expression levels of other IAP family members or B-cell lymphoma 2 (BCL-2) related proteins. YM155 also suppresses proliferation in a broad range of human cancer cell lines, induces tumor regression in non-small cell lung cancer (NSCLC), melanoma, bladder, aggressive non-Hodgkin lymphoma, and breast cancer xenograft models, reduces spontaneous metastases, and significantly prolongs the survival of animal harboring established metastatic tumors derived from a human triple-negative breast cancer (TNBC) cell lines.
CAS No	355406-09-6
Molecular Weight	398.84
Purity	0.98
Storage	Store at -20°C
Synonyms	YM155 hydrochloride; YM 155 hydrochloride
Targets	survivin
IC50	0.54 nM
Molecular Formula	C20H19ClN4O3
Chemical Name	1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione; chloride
Solubility	Soluble to 55 mg/ml in DMSO and to 89 mg/ml in water
Shipping Conditions	Evaluation sample solution: ship with blue ice. All other available size: ship with RT, or blue ice upon request
category	Specialty Chemicals(c26)
cas_num	355406-09-6

Basic Info

Product Name:

1-(2-Methoxyethyl)-2-Methyl-4,9-dioxo-3-(pyrazin-2-ylMethyl)-4,9-dihydro-1H-naphtho[2,3-d]iMidazol-3-iuM chloride

Other Name:

1-(2-Methoxyethyl)-2-Methyl-4,9-dioxo-3-(pyrazin-2-ylMethyl)-4,9-dihydro-1H-naphtho[2,3-d]iMidazol-3-iuM chloride;YM 155 hydrochloride;YM-155 (hydrochloride);YM155 hydrochloride;YM-155 HCl;YM155 HYDROCHLORIDE;YM 155 HYDROCHLORIDE;YM-155 (chloride);YM-155 HCl (Sepantronium HCl)

CAS No.:

355406-09-6

Molecular Formula:

C20H19ClN4O3

InChIKeys:

NUZWGSASIPTGSA-UHFFFAOYSA-M

Molecular Weight:

398.85

Exact Mass:

398.1145682

DSSTox ID:

DTXSID40630623

Color/Form:

Light brown to brown

Categories:

Characteristics

Critical Temperature & Pressure:

Store at -20°C

Seller Information

Business Type:
Manufactory

Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase

Location:
Shirley, New York 11967, USA

Payment Terms:
TT against copy of documents,D/P

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Year of Establishment:
2004

Creative Enzymes is a leading Manufactory supplier of Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl- based in America. With a commitment to quality and customer satisfaction, Creative Enzymes has become a trusted name in the industry. Our product line includes a range of high-quality Proline dipeptidase, Glucoamylase, BenzaMide, N-1H-pyrrolo[2,3-c]pyridin-5-yl-, which are available at competitive prices. Creative Enzymes has established itself as a reliable supplier of chemical products on the echemi.com.
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YM-155 hydrochloride

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