GSK1016790A
942206-85-1
98%
2026-07-24
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Product Description
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Seller Information
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Description
ProductName GSK1016790A Cat No COEC-115 Description GSK1016790A is a novel and potent TRPV4 channel agonist. The TRPV4 (transient receptor potential vanilloid 4) member of the TRP superfamily has been implicated in numerous physiological processes. GSK1016790A elicited Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300 fold more potent than 4a-PDD. Applications A novel and potent TRPV4 channel agonist Form Solid CAS No 942206-85-1 Molecular Weight 655.61 Purity ≥98% Synonyms (N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide Molecular Formula C28H32Cl2N4O6S2 Solubility Soluble in DMSO >10 mg/mL Refractive Index 1.53 (Predicted) Density 1.12 g/cm3 (Predicted) category Specialty Chemicals(c26) cas_num 942206-85-1 Basic Info-
Product Name:
GSK 10116790A
Other Name:Benzo[b]thiophene-2-carboxamide,N-[(1S)-1-[[4-[(2S)-2-[[(2,4-dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]-;N-[(1S)-1-[[4-[(2S)-2-[[(2,4-Dichlorophenyl)sulfonyl]amino]-3-hydroxy-1-oxopropyl]-1-piperazinyl]carbonyl]-3-methylbutyl]benzo[b]thiophene-2-carboxamide;GSK 1016790A;N-[(1S)-1-[[4-[(2S)-2-[[(2,4-Dichlorophenyl)sulfonyl]amino]-3-hydroxypropanoyl]-1-piperazinyl]carbonyl]-3-methylbutyl]-1-benzothiophene-2-carboxamide;GSK 10116790A
CAS No.:942206-85-1
Molecular Formula:C28H32Cl2N4O6S2
InChIKeys:InChIKey=IVYQPSHHYIAUFO-VXKWHMMOSA-N
Molecular Weight:655.6
Exact Mass:655.61
DSSTox ID:DTXSID30635248
Categories:
Characteristics -
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Seller Information
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Business Type:
Manufactory
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Main Products:
Coenzymes,Inhibito,Enzymes,Zymogens,Substrates,Native Microorganism Creatine Amidinohydrolase
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Location:
Shirley, New York 11967, USA
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Payment Terms:
TT against copy of documents,D/P
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Average lead Time:
15
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Total Annual Revenue:
$1 million-$2.5 million
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Year of Establishment:
2004
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