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Loratadine 99% powder  Dideu buy - large image1
Loratadine 99% powder  Dideu buy - image1

Loratadine 99% powder Dideu

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

79794-75-5

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Ang port in China

Brand:

Dideu

Packaging:

25Kg/Drum

Price valid (until):

2023-01-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Our Reference Specification, for more details, pls contact us for COA, MSDS and certification:
    Email & Skype: Service@dideu.com Telephone:+86-29-89586680
    Mobile:+86-15129568250; Whatsapp&Wechat: +8615129568250

    ItemStandardTest Results
    IdentificationA.H-NMR:Comply with the structureComplies
    B.LC-MS:Comply with the structureComplies
    C.The IR spectrum of sample should be identical with that of reference standard.Complies
    D.HPLC-ESI-MSComplies
    The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
    Loss on drying≤2.0%0.19%
    Heavy metals≤10 ppm<10ppm
    Water≤1.0%0.10%
    Sulphated ash≤0.5% determined on 1.0 g.0.01%
    Residue on ignition≤0.1%0.03%
    Related SubstancesUnspecified impurities: for each impurity ≤0.10%<0.10%
    Total Impurity ≤0.5%0.18%
    Purity≥99.0%99.70%
    Assay99.0%~101.0% (anhydrous substance).99.80%
    StoragePreserve in well-closed, light-resistant and airtight containers.Complies

    Our normal packaging is 25kgs/Drum and 200kgs/Drum.
    The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.

    a) Free sample can be supplied.
    b) Guide our clients by professional knowledge and teach them how to use our product after sales.
    c) Accept SGS, BV any other third-party inspection before loading.
    d) High quality best price Guaranteed.

    Why do you choose Dideu Industries as your partner?
    A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.
    B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.
    C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.
    D) Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.

    ECHEMI Editorial Reference
    Loratadine(SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.IC50 value: 32 uMTarget: H1-receptorLoratadine is a non-sedative antihistamine that inhibits histamine-induced activities of IL-6 and IL-8 secretion in endothelial cells.
    Solid
    Loratadine is a benzocycloheptapyridine. It has a role as a geroprotector.|Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.|Loratadine and its metabolic derivative desloratadine are second generation antihistamines that are used for the treatment of allergic rhinitis, angioedema and chronic urticaria. Loratadine and desloratadine have been linked to rare, isolated instances of clinically apparent acute liver injury.|Loratadine is a piperidine histamine H1-receptor antagonist with anti-allergic properties and without sedative effects. Loratadine blocks the H1 histamine receptor and prevents the symptoms that are caused by histamine activity on capillaries, bronchial smooth muscle, and gastrointestinal smooth muscle, including vasodilatation, increased capillary permeability, bronchoconstriction, and spasmodic contraction of gastrointestinal smooth muscle. Loratadine does not cross the blood-brain barrier and does not cause central nervous system effects.|A second-generation histamine H1 receptor antagonist used in the treatment of allergic rhinitis and urticaria. Unlike most classical antihistamines (HISTAMINE H1 ANTAGONISTS) it lacks central nervous system depressing effects such as drowsiness.

    Basic Info
    Product Name:

    Loratadine

    Other Name:

    1-Piperidinecarboxylic acid,4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-,ethyl ester;11H-Benzo[5,6]cyclohepta[1,2-b]pyridine,1-piperidinecarboxylic acid deriv.;Sch 29851;Loratadine;Loratidine;Klaritin;Claritin;Bonalerg;Civeran;Anhissen;Claritine;Clarityn;Claratyne;Cronopen;Fristamin;Histaloran;Lertamine;Lisino;Loracert;Clarityne;Loranox;Lorastine;Loratyne;Lorfast;Lowadina;Optimin;Polaratyne;Pylor;Restamine;Sensibit;Sohotin;Tadine;Velodan;Zeos;Loradex;Alavert;Flonidan;Klarifer;Clarotadin;Erolin;Lomilan;Symphoral

    CAS No.:

    79794-75-5

    Molecular Formula:

    C22H23ClN2O2

    InChIKeys:

    InChIKey=JCCNYMKQOSZNPW-UHFFFAOYSA-N

    Molecular Weight:

    382.88

    Exact Mass:

    382.88

    EC Number:

    1308068-626-2

    UNII:

    7AJO3BO7QN

    NSC Number:

    758628|721075

    DSSTox ID:

    DTXSID2023224

    NCI Thesaurus Code:

    C29162

    Color/Form:

    Crystals from acetonitrile

    ATC Code:

    R06AX13|R - Respiratory system

    HScode:

    2933990090

    Characteristics
    PSA:

    42.4

    XLogP3:

    5.2

    Appearance:

    white powder

    Density:

    1.3±0.1 g/cm3

    Melting Point:

    134-136 °C

    Boiling Point:

    531.3°C at 760 mmHg

    Flash Point:

    275.1±30.1 °C

    Refractive Index:

    1.614

    Water Solubility:

    It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.

    Storage Conditions:

    2-8°C

    Collision Cross Section:

    187.4 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)]|185.8 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Skin sensitization, Category 1

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    Germ cell mutagenicity, Category 2

    Carcinogenicity, Category 2

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    H341 Suspected of causing genetic defects

    H351 Suspected of causing cancer

    H400 Very toxic to aquatic life

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    P273 Avoid release to the environment.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    P318 IF exposed or concerned, get medical advice.

    P391 Collect spillage.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

    Location:

    https://www.dideu.com/en/

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2016

    Certifications:

    ISO Certificate,REACH

    Company Profile
    ">Company Profile
  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Loratadine

    20 KG May 16, 2025
    Post an enquiry for this product
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