Salcaprozate sodium,SNAC 98.0%~102.0% as an oral absorption enhancer for Semaglutide
27 Inquiries
203787-91-1
Pharmaceutical Grade
98%
Dalian
HDC
1Kg per aluminum foil bag
2023-01-31
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine
-
Product Description
-
Seller Information
-
Inquiry History
-
DescriptionECHEMI Editorial ReferenceSalcaprozate Sodium is the sodium salt form of salcaprozate, an oral absorption promoter. Salcaprozate sodium may be used as a delivery agent to promote the oral absorption of certain macromolecules with poor bioavailability such as insulin and heparin.
It is a white to off-white crystalline powder, and its solubility in water is approximately 33 mg/mL.
Salcaprozate Sodium (SNAC) is a synthetic N-acetylated amino-acid derivative of salicylic acid. SNAC is a weak acid that display amphiphilicity and surface activity. It was discovered as part of a screen to identify carrier-based PEs that could “chaperone” poorly permeable payloads across the intestine. This compound is the most extensively tested carrier and the only PE approved in an oral formulation designed to improve oral BA, albeit with a small molecule, cyanocobalamin/SNAC. In other preclinical studies, it also improved intestinal permeation of peptides (salmon calcitonin (sCT) and insulin), along with poorly permeable small molecules (e.g., cromolyn). SNAC was tested in many formats: taste-masked liquids, tablets, and soft gelatin capsules. Similar to C10, SNAC can be blended with the active pharmaceutical ingredient (API) using conventional processes, which makes manufacturing uncoated oral tablet dosage forms economic and relatively easy to scale[1].Basic Info-
Product Name:
Salcaprozate Sodium
Other Name:sodium,8-[(2-hydroxybenzoyl)amino]octanoate;Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt;SNAC,sodium 8-[(2-hydroxybenzoyl)amino]octanoate;Salcaprozate sodium;Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, sodium salt;2,5-Furandione,3-chlorodihydro-,(7R)-;N-[8-(2-Hydroxybenzoyl)amino]caprylic acid, disodium salt;Chlorotoluron Impurity 3
CAS No.:203787-91-1
Molecular Formula:C15H22NNaO4
InChIKeys:OBKUJEVXEMKQMJ-UHFFFAOYSA-N
Molecular Weight:303.33
Exact Mass:301.12900240
EC Number:231-019-4
UNII:1YTW0422YU
DSSTox ID:DTXSID50174306
NCI Thesaurus Code:C75026
Color/Form:White to Off-White
Categories:
Characteristics-
Melting Point:
183 - 185°C
Critical Temperature & Pressure:Inert atmosphere,Room Temperature
Research-
Class:
GLP-1R agonist
Status:FDA-approved (Ozempic / Wegovy / Rybelsus)
Mechanism:Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.
Activity note:Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).
Source:Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI
Clinical Development:FDA:Ozempic, Wegovy, Rybelsus (approved 2017-12-05)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Literature:
NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)
Disclaimer:Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine
-
Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China
-
Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
15 days
-
Total Annual Revenue:
$5 million-$10 million
-
Total Employees:
51-100
-
Year of Establishment:
2020
-
-
Inquiry History27 Inquiries
Country Product Purchase Quantity Date Posted
India
Salcaprozate Sodium
1 KG Feb 13, 2026
India
Salcaprozate sodium
1 KG May 8, 2024
Tunisia
Salcaprozate de sodium (SNAC)
1 MT May 4, 2026
India
Salcaprozate Sodium
1 KG Jul 20, 2026
Italy
Sodium Salcaprozate (SNAC)
250 G Apr 17, 2026
Pakistan
SALCAPROZATE SODIUM SNAC
450 KG Apr 10, 2026
United States
Salcaprozate Sodium
500 KG Feb 18, 2026
United States
Salcaprozate Sodium/ SNAC 99%
10 KG Feb 13, 2026
Pakistan
SALCAPROZATE SODIUM
500 KG Feb 11, 2026
South Africa
Salcaprozate Sodium
1 MT Oct 12, 2023
Pakistan
SALCAPROZATE SODIUM
600 KG Jan 28, 2026
United States
Salcaprozate Sodium
1 KG Nov 26, 2025
Bangladesh
Salcaprozate Sodium-GMP
500 KG Nov 21, 2024
United States
Salcaprozate Sodium
10 KG Sep 14, 2024
Russia
salcaprozate sodium
20 KG Jan 18, 2024
United Kingdom
Salcaprozate Sodium -----the supporting excipient of Semaglutide
5 KG Nov 17, 2023
India
Salcaprozate sodium
1 KG Oct 7, 2023
Pakistan
SALCAPROZATE SODIUM
180 KG Jul 20, 2026
United Kingdom
Salcaprozate Sodium
1 MT Jul 17, 2026
Pakistan
SALCAPROZATE SODIUM
50 KG Jun 5, 2026 Post an enquiry for this product
More from this Seller
-
-
-
China Quality Manufacturer Supply Thymalin 10mg Peptide with Best Price
Pharmaceutical Grade / 99%
$7.8-8.1/UNIT FOB
-
-
-
-
Neohesperidin Dihydrochalcone (NHDC), CAS No.: 20702-77-6
Food Grade / 98.0%
-
-
-
-
C9-11 PARETH-6(91-6) Clear to slight hazy liquid HANDOM CHEM
Cosmetics Grade
-
-
-
-
China Origin Klow Blend 80mg Lyophilized Powder Used for Tissue Regeneration and Anti-Inflammatory
Pharmaceutical Grade / 99.00%
-