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Home > Natural Products > Alkaloids > Cytisine for Sale > CYTISINE & SOPHORINE & LABURNIN 99% light yellow powder Dideu
CYTISINE & SOPHORINE & LABURNIN 99% light yellow powder  Dideu buy - large image1
CYTISINE & SOPHORINE & LABURNIN 99% light yellow powder  Dideu buy - image1

CYTISINE & SOPHORINE & LABURNIN 99% light yellow powder Dideu

1 Inquiries

Unit Price: Get Latest Price
CAS No.:

485-35-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShangHai

Brand:

Dideu

Packaging:

25kg/Cardboard Drum

Sample Available:

Yes

Price valid (until):

2023-01-28

Company Type:
Manufactory
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    Our Reference Specification, for more details, pls contact us for COA, MSDS and certification:

    Email & Skype: Service@dideu.com Telephone:+86-29-89586680

    Mobile:+86-15129568250; Whatsapp&Wechat: +8615129568250



    Item

    Standard

    Test Results

    Identification

    A.H-NMR:Comply with the structure

    Complies

    B.LC-MS:Comply with the structure

    Complies

    C.The IR spectrum of sample should be identical with that of reference standard.

    Complies

    D.HPLC-ESI-MS

    Complies

    The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

    Loss on drying

    ≤2.0%

    0.19%

    Heavy metals

    ≤10 ppm

    <10ppm

    Water

    ≤1.0%

    0.10%

    Sulphated ash

    ≤0.5% determined on 1.0 g.

    0.01%

    Residue on ignition

    ≤0.1%

    0.03%

    Related Substances

    Unspecified impurities: for each impurity ≤0.10%

    <0.10%

    Total Impurity ≤0.5%

    0.18%

    Purity

    ≥99.0%

    99.70%

    Assay

    99.0%~101.0% (anhydrous substance).

    99.80%

    Storage

    Preserve in well-closed, light-resistant and airtight containers.

    Complies





    The packaging can be customized. the shipping term can be by sea, by air, and sample or small quantity can be shipped by DHL, FEDEX, EMS and TNT.


    a) Free sample can be supplied.

    b) Guide our clients by professional knowledge and teach them how to use our product after sales.

    c) Accept SGS, BV any other third-party inspection before loading.

    d) High quality best price Guaranteed.

    Why do you choose Dideu Industries as your partner?

    A) High quality can be guaranteed. Dideu Industries since 1975 are reputed chemical manufacturer and are Certified by ISO 9001;2015 and have GMP certification.Free sample can be arranged before shipment and SGS,BV and other third party inspection company are accepted before loading.For regular customers, we accept L/C 180 Days, D/P,D/A payment term. If there is any quality problem after goods arrive. Dideu Industries will do fully payment refund.

    B) Best price can be guaranteed. As Dideu Industries are integrated pharmaceuticals and chemicals producer, the production cost can be controlled and price will be definitely more competitive than China trading companies.

    C) Professional enginners from Dideu Industries will give professional usage guide and services after sales.

    D) Dideu Industries work 7×24 hours and your request will be processed by our professional staff in different shift period.


    ECHEMI Editorial Reference
    Cytisine is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus. Cytisine is a partial agonist of α4β2 nAChRs[1], and partial to full agonist at β4 containing receptors and α7 receptors[2]. has been used medically to help with smoking cessation[3].
    Cytisine is an organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking. It has a role as a nicotinic acetylcholine receptor agonist, a phytotoxin and a plant metabolite. It is an alkaloid, an organic heterotricyclic compound, a secondary amino compound, a lactam and a bridged compound.|Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus. Recent studies have shown it to be a more effective and significantly more affordable smoking cessation treatment than nicotine replacement therapy. Also known as baptitoxine or sophorine, cytisine has been used as a smoking cessation treatment since 1964, and is relatively unknown in regions outside of central and Eastern Europe. Cytisine is a partial nicotinic acetylcholine agonist with a half-life of 4.8 hours. Recent Phase III clinical trials using Tabex (a brand of Cytisine marketed by Sopharma AD) have shown similar efficacy to varenicline, but at a fraction of the cost.

    Basic Info
    Product Name:

    Cytisine

    Other Name:

    1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,1,2,3,4,5,6-hexahydro-,(1R,5S)-;Cytisine;1,5-Methano-8H-pyrido[1,2-a][1,5]diazocin-8-one,1,2,3,4,5,6-hexahydro-,(1R)-;(1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one;Baptitoxin;Baptitoxine;Cytiton;Cytitone;Sophorine;Ulexine;Tabex;Ulexin;Laburnin;Sophorin;(-)-Cytisine;Cytisin;Tsitafat;Cytisinicline;3728-36-7;1267572-93-9;1932311-41-5;1933793-08-8;2308481-87-8

    CAS No.:

    485-35-8

    Molecular Formula:

    C11H14N2O

    InChIKeys:

    InChIKey=ANJTVLIZGCUXLD-UHFFFAOYSA-N

    Molecular Weight:

    190.24

    Exact Mass:

    190.24

    EC Number:

    207-616-0

    UNII:

    53S5U404NU

    NSC Number:

    407282

    Color/Form:

    Orthorhombic prisms from acetone|Solid

    ATC Code:

    N - Nervous system

    HScode:

    2933990090

    Categories:

    Alkaloids

    Characteristics
    PSA:

    32.3

    XLogP3:

    0.2

    Appearance:

    light yellow powder

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    152-153 °C

    Boiling Point:

    218 °C @ Press: 2 Torr

    Flash Point:

    203.6±25.7 °C

    Refractive Index:

    1.623

    Water Solubility:

    439g/L(16 ºC)

    Storage Conditions:

    Store at RT

    Vapor Pressure:

    7.61X10-6 mm Hg at 25 deg C (est)

    Toxicity:

    LD50 in mice (mg/kg): 1.73 i.v.; 9.4 i.p.; 101 orally (Barlow, McLeod)

    Specific rotation:

    D17 -120°

    Henrys Law Constant:

    Henry's Law constant = 4.01X10-12 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    pK1 = 6.11; pK2 = 13.08

    Collision Cross Section:

    137.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Deliquescent crystals, soluble in water and alchol. pH of 0.1 molar aqueous solution = 4.3 /Cytisine hydrochloride/|Hydroxyl radical reaction rate constant = 8.59X10-11 cu cm/molec-sec at 25 °C (est)

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    In original packages, in dry, and light-protected premises at temperature of 15 deg C to 25 deg C (60 - 75 deg F)

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

    Location:

    https://www.dideu.com/en/

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2016

    Company Certificates
    • Shaanxi Dideu Medichem Co. LtdISO Certificate ISO Certificate
    • Shaanxi Dideu Medichem Co. LtdREACH REACH
    Company Profile
    ">Company Profile
  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Cytisine

    5  Feb 1, 2024
    Post an enquiry for this product
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