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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Calcipotriol for Sale > Calcipotriene anhydride 112965-21-6
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Calcipotriene anhydride 112965-21-6

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CAS No.:

112965-21-6

Grade:

Pharmaceutical Grade

Content:

99%

Brand:

Zison

Packaging:

foil bag

Price valid (until):

2023-02-28

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Avatrombopag,Lenvatinib,Safinamide mesylate,Axitinib

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Carbotriol, a derivative of vitamin D, binds to cell surface VD3 receptors to regulate intracellular DNA and keratin synthesis, inhibiting the overproliferation of skin cells (keratinocytes) and inducing their differentiation, thus correcting the abnormal proliferation and differentiation of psoriatic skin cells. It also regulates the release of cellular inflammatory factors, inhibits inflammatory infiltration and proliferation, and acts as an anti-inflammatory agent. It is more effective in the treatment of psoriasis in specific areas such as the scalp.

    ItemsSpecifications
    Molecular formulaC27H40O3
    Molecular weight412.6
    Melting Point166-168°C

    Basic Info
    Product Name:

    Calcipotriol

    Other Name:

    1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,(1R,3S,5Z)-;9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol,24-cyclopropyl-,(1α,3β,5Z,7E,22E,24S)-;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol;MC 903;Calcipotriol;Dovonex;Daivonex;Calcipotriene;Calciptriol;Psorcutan;PRI 2201;112828-00-9

    CAS No.:

    112965-21-6

    Molecular Formula:

    C27H40O3

    InChIKeys:

    InChIKey=LWQQLNNNIPYSNX-UROSTWAQSA-N

    Molecular Weight:

    412.6

    Exact Mass:

    412.60

    EC Number:

    1806241-263-5

    DSSTox ID:

    DTXSID0046648

    HScode:

    2906195000

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    60.69000

    XLogP3:

    5.43

    Appearance:

    white crystalline solid

    Density:

    1.12±0.1 g/cm3(Predicted)

    Melting Point:

    166-168 °C

    Boiling Point:

    582.0±50.0 °C(Predicted)

    Flash Point:

    250.6±24.7 °C

    Refractive Index:

    1.580

    Water Solubility:

    DMSO: soluble15mg/mL, clear

    Storage Conditions:

    Desiccate at -20°C

    Vapor Pressure:

    5.74E-16mmHg at 25°C

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 2, Oral

    Acute toxicity - Category 3, Dermal

    Acute toxicity - Category 2, Inhalation

    Specific target organ toxicity – repeated exposure, Category 1

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H300 Fatal if swallowed

    H311 Toxic in contact with skin

    H330 Fatal if inhaled

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P284 [In case of inadequate ventilation] wear respiratory protection.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P316 Get emergency medical help immediately.

    P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P320 Specific treatment is urgent (see ... on this label).

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Avatrombopag,Lenvatinib,Safinamide mesylate,Axitinib

    Location:

    Room 410, Building 9, No. 2566, Century Avenue, Jinan, 250104, China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2021

    Certifications:

    business license,ISO

    Zison Pharma,a leading manufacturer of APIs and pharma intermediates(Axitinib and intermediates, Avatrombopag and intermediates,Finerenone and intermediates,Lenvatinib and intermediates,Tenofovir alafenamide hemifumarate and intermediates,Safinamide and intermediates,Crizotinib and intermediates, Roxadustat and intermediates, Calcipotriene monohydrate and intermediates etc.)based in Jinan, China. With 10 years of experience in the APIs and pharma intermediates field, we understand that quality and service is the key to win in the fast-changing market and our client's success is our success,which is why in our customer relations we always put the needs of our clients first.
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