 Home > Encyclopedia > Calcipotriol

Calcipotriol

Calcipotriol structure

CAS No:
112965-21-6
Formula:
C27H40O3
Chemical Name:
Calcipotriol
Synonyms:
1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,(1R,3S,5Z)-;9,10-Secochola-5,7,10(19),22-tetraene-1,3,24-triol,24-cyclopropyl-,(1α,3β,5Z,7E,22E,24S)-;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-Cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanediol;MC 903;Calcipotriol;Dovonex;Daivonex;Calcipotriene;Calciptriol;Psorcutan;PRI 2201;112828-00-9
Categories:
Active Pharmaceutical Ingredients > Specialty Drugs

Description

White Crystalline SolidCalcipotriol is a topical vitaminD3 derivative effective in the treatment of psoriasis vulgaris. The drug acts by binding to vitamin D3 receptors in the skin keratinocytes, producing an elevation in cell differentiation and a reduction in cell proliferation. Although its efficacy is comparable to calcitriol, calcipotriol exhibits at least 100 times less effect on calcium metabolism in rats.

Calcipotriol Basic Attributes

Molecular Weight：

412.6

Exact Mass：

412.60

EC Number：

1806241-263-5

DSSTox ID：

DTXSID0046648

HScode：

2906195000

Characteristics

PSA：

60.69000

XLogP3：

5.43

Appearance：

white crystalline solid

Density：

1.12±0.1 g/cm3(Predicted)

Melting Point：

166-168 °C

Boiling Point：

582.0±50.0 °C(Predicted)

Flash Point：

250.6±24.7 °C

Refractive Index：

1.580

Water Solubility：

DMSO: soluble15mg/mL, clear

Storage Conditions：

Desiccate at -20°C

Vapor Pressure：

5.74E-16mmHg at 25°C

Safety Information

Transport codes：

UN 2811 6.1 / PGIII

wgk germany：

hazard class code：

36/37/38

safety instructions：

Marks：

GHS Classification：

|Danger|H300 (75%): Fatal if swallowed [Danger Acute toxicity, oral]|P201, P260, P261, P262, P263, P264, P270, P271, P280, P284, P301+P310, P302+P350, P302+P352, P304+P340, P305+P351+P338, P308+P313, P310, P312, P314, P320, P321, P322, P330, P332+P313, P337+P313, P361, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 4 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]|P260, P264, P270, P271, P280, P284, P301+P310, P302+P352, P304+P340, P310, P312, P314, P320, P321, P322, P330, P361, P363, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.

Calcipotriol Use and Manufacturing

A labelled antipsoriatic. A vitamin D3 analogue with low calcemic activity.

Computed Properties

Molecular Weight:412.6
XLogP3:4.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:412.29774513
Monoisotopic Mass:412.29774513
Topological Polar Surface Area:60.7
Heavy Atom Count:30
Complexity:743
Undefined Atom Stereocenter Count:7
Undefined Bond Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Calcipotriol

HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
YRS

Business licensed

Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Calcipotriene

CAS No.: 112965-21-6

Content: 99.00%

Inquiry
Wuhan Pnq Int Trade Co., Ltd Contact Supplier

CN
YRS

Business licensed

Trader Supplier of Apigenin,PQQ,NMNH

High Purity EP Standard Calcipotriol CAS 112965-21-6/112828-00-9 Calcipotriene

Unit Price: nullnull /null null

CAS No.: 112965-21-6

Grade: Chemical Grade

Content: 99%

Inquiry
Shandong Ailike New Material Technology Contact Supplier

CN
YRS

Business licensed

Trader Supplier of API,Antibiotics,Anti cancer category

Calcipotriene cas 112965-21-6

Unit Price: $50 /MT EXW

CAS No.: 112965-21-6

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Hangzhou Runyan Pharma Technology Co.,Ltd. Contact Supplier

CN
YRS

Business licensed

Trader Supplier of Retatrutide

Calcipotriene/Calcipotriol

Unit Price: nullnull /null null

CAS No.: 112965-21-6

Grade: Pharmaceutical Grade

Content: 99%

Inquiry
Henan Lihao Chem Plant Limited Contact Supplier

CN
YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

Calcipotriol 99% see COA Kanbei kanbei

Unit Price: nullnull /null null

CAS No.: 112965-21-6

Grade: Industrial Grade

Content: 99%

Inquiry

Learn More Other Chemicals

Calcipotriol Monohydrate

147657-22-5
Chromic acid (H2CrO4), disodium salt, tetrahydrate

10034-82-9
Aluminum sulfate

10043-01-3
HMPAO Formula

105613-48-7
Adapalene Formula

106685-40-9
Tazarotene Formula

118292-40-3
calcium trisodium pentetate Structure

12111-24-9
Indium chloride Structure

12672-70-7
What is Verteporfin

129497-78-5
What is MTS Reagent

138169-43-4

Hot Searches: tirzepatide peptide 30mg for sale; retatrutide peptide purchase; dienoget; acetic acid price; dextroamphetamine sulfate; good research chemical sites

Guide of Calcipotriol

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Learn More Other Chemicals

Calcipotriol

SDS

Request for Quotation



Feedback & Suggestions

Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.