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Crizotinib 99% 877399-52-5

Name: Crizotinib 99% 877399-52-5
Brand: Zison
SKU: pr2302061384
Price: 3135 USD
Availability: InStock

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CAS No.:

877399-52-5

Grade:

Pharmaceutical Grade

Content:

99%

Brand:

Zison

Packaging:

Foil bag

Price valid (until):

2023-02-28

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Zison Pharmaceutical (Shandong)Co.,Ltd.

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Avatrombopag,Lenvatinib,Safinamide mesylate,Axitinib

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Crizotinib, chemical name is 3-[(R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidine- 4-yl)-1H-pyrazol-4-yl] pyridin-2-amine, it is white to light yellow powder. It is primarily indicated for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) positive for anaplastic lymphoma kinase (ALK) as determined by approved test.

Items	Specifications
Appearance	white to tan powder
molecular formula	C21H22Cl2FN5O
Storage conditions	room temp

Certificates

Basic Info

Product Name:

Crizotinib

Other Name:

2-Pyridinamine,3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-;3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine;[3-[[(R)-1-(2,6-Dichloro-3-fluorophenyl)ethyl]oxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-yl]amine;PF 2341066;PF 02341066;Crizotinib;(R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-ylamine;Xalkori;3-((R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine;912279-98-2

CAS No.:

877399-52-5

Molecular Formula:

C21H22Cl2FN5O

InChIKeys:

InChIKey=KTEIFNKAUNYNJU-GFCCVEGCSA-N

Molecular Weight:

450.343

Exact Mass:

450.34

EC Number:

1308068-626-2

UNII:

53AH36668S

NSC Number:

749005

NCI Thesaurus Code:

C74061

ATC Code:

L01XE16|L - Antineoplastic and immunomodulating agents

HScode:

29333990

Categories:

Antineoplastic Agents

Characteristics

PSA:

XLogP3:

3.7

Density:

1.5±0.1 g/cm3

Melting Point:

192 °C

Boiling Point:

599.177°C at 760 mmHg

Flash Point:

316.2±30.1 °C

Refractive Index:

1.673

See More Crizotinib Properties 

Hazard Identification

Classification of the substance or mixture

Skin sensitization, Category 1

Eye irritation, Category 2

Germ cell mutagenicity, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H317 May cause an allergic skin reaction H319 Causes serious eye irritation H341 Suspected of causing genetic defects H400 Very toxic to aquatic life
Prevention	P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P264 Wash ... thoroughly after handling. P203 Obtain, read and follow all safety instructions before use. P273 Avoid release to the environment.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P318 IF exposed or concerned, get medical advice. P391 Collect spillage.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Crizotinib Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Avatrombopag,Lenvatinib,Safinamide mesylate,Axitinib

Location:
Room 410, Building 9, No. 2566, Century Avenue, Jinan, 250104, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2021

Certifications:
business license,ISO

Zison Pharma,a leading manufacturer of APIs and pharma intermediates(Axitinib and intermediates, Avatrombopag and intermediates,Finerenone and intermediates,Lenvatinib and intermediates,Tenofovir alafenamide hemifumarate and intermediates,Safinamide and intermediates,Crizotinib and intermediates, Roxadustat and intermediates, Calcipotriene monohydrate and intermediates etc.)based in Jinan, China. With 10 years of experience in the APIs and pharma intermediates field, we understand that quality and service is the key to win in the fast-changing market and our client's success is our success,which is why in our customer relations we always put the needs of our clients first.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	Wholesale Crizotinib Raw Material Powder 99% White Powder CAS 877399-52-5 Crizotinib Powder	50 KG	Nov 19, 2023
Pakistan	Crizotinib	1 KG	Jun 20, 2025

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