CITICOLINE, CYTIDINE 5'-DIPHOSPHOCHOLINE,CDP-Coline 98.0% white or almost white crystalline powder
ISO 8 Inquiries
987-78-0
Pharmaceutical Grade
98%
Shanghai
25KG/Cardboard drum
Yes
2023-02-28
Adenosine,D-ribose,2-chloroadenosine,N4-Acetylcytosine,Guanine,6-Tetra-O-Benzyl-D-Glucopyranose
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceCiticoline is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.
Solid
CDP-choline is a member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes. It has a role as a human metabolite, a psychotropic drug, a neuroprotective agent, a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is a member of phosphocholines and a member of nucleotide-(amino alcohol)s. It derives from a CDP. It is a conjugate base of a CDP-choline(1+).|Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.|Citicoline is a nutritional supplement and source of choline and cytidine with potential neuroprotective and nootropic activity. Citicoline, also known as cytidine-5-diphosphocholine or CDP-choline, is hydrolyzed into cytidine and choline in the intestine. Following absorption, both cytidine and choline are dispersed, utilized in various biosynthesis pathways, and cross the blood-brain barrier for resynthesis into citicoline in the brain, which is the rate-limiting product in the synthesis of phosphatidylcholine. This agent also increases acetylcholine (Ach), norepinephrine (NE) and dopamine levels in the central nervous system (CNS). In addition, citicoline is involved in the preservation of sphingomyelin and cardiolipin and the restoration of Na+/K+-ATPase activity. Citicoline also increases glutathione synthesis and glutathione reductase activity, and exerts antiapoptotic effects.|Donor of choline in biosynthesis of choline-containing phosphoglycerides.CertificatesBasic Info-
Product Name:
Cytidine diphosphate choline
Other Name:Cytidine 5′-(trihydrogen diphosphate),P′-[2-(trimethylammonio)ethyl] ester,inner salt;Cytidine 5′-(trihydrogen diphosphate),P′-[2-(trimethylammonio)ethyl] ester,hydroxide,inner salt;Choline,hydroxide,5′-ester with cytidine 5′-(trihydrogen pyrophosphate),inner salt;Cytidine 5′-diphosphate choline;Citicoline;Cytidine diphosphate choline ester;Nicholin;Niticolin;Cereb;Colite;Nicolin;Recofnan;Ensign;Suncholin;CDP-choline;Cytidine diphosphate choline;Cytidine diphosphorylcholine;Cytidine diphosphocholine;Cytidine 5′-diphosphocholine;Cytidine 5′-(cholinyl pyrophosphate);Cytidine choline diphosphate;Cytidine 5′-(choline diphosphate);Choline 5′-cytidine diphosphate;Recognan;Choline cytidine diphosphate;Citicholine;Cytidoline;Citidoline;Somazina;Somazine;Reagin;Neucolis;Difosfocin;Sintoclar;Haocolin;Corenalin;Audes;Rexort;Citifar;Hornbest;Cyscholin;Emicholine F;NSC 122002;Cognizin;1477-47-0;64143-42-6;769081-33-6
CAS No.:987-78-0
Molecular Formula:C14H26N4O11P2
InChIKeys:InChIKey=RZZPDXZPRHQOCG-OJAKKHQRSA-N
Molecular Weight:488.32
Exact Mass:488.107330
EC Number:213-580-7
DSSTox ID:DTXSID9048431
NCI Thesaurus Code:C96743
ATC Code:N - Nervous system
HScode:2942000000
Categories:
Characteristics-
PSA:
214
XLogP3:-7.07
Appearance:Solid
Boiling Point:851.4°C at 760 mmHg
Toxicity:LD50 in mice, rats (mg/kg): 4600 ±335, 4150 ±370 i.v.; both species 8 g/kg orally (Grau)
Specific rotation:D25 +19.0° (c = 0.86 in H2O)
Collision Cross Section:197.6 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|200.64 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|198.86 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|208.98 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|208.41 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|198.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|207.8 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|205.9 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|210.2 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|207.7 Ų [M-H]-
Hazard IdentificationClassification of the substance or mixture
Not classified.
GHS label elements, including precautionary statements
Pictogram(s) No symbol. Signal word No signal word
Hazard statement(s) none
Precautionary statement(s) Prevention none
Response none
Storage none
Disposal none
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Adenosine,D-ribose,2-chloroadenosine,N4-Acetylcytosine,Guanine,6-Tetra-O-Benzyl-D-Glucopyranose
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Location:
Hongqi Area, Xinxiang city, Henan province, China
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Payment Terms:
TT against copy of documents,L/C,D/A
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Average lead Time:
7 days
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Total Annual Revenue:
$1 million-$2.5 million
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Total Employees:
11-50
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Year of Establishment:
2017
Company Certificates-
OHSAS18001
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ISO14001
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ISO9001
Xinxiang Aurora Biotechnology Co., Ltd. is located in Xinxiang city of Henan Province, which is an important nucleoside and nucleotide raw material supply base in domestic.
We are professional chemical Enterprises including development, production, sales and service of bio-engineering product, business scope involving fine chemicals, pharmaceutical intermediates, optoelectronic materials and water purification materials and other fields. So far, we have made a series of breakthroughs in the nucleoside, nucleotide industrial production and related derivatives development.
Aurora Biotechnology has more than 80 employees, our R & D team including lot of doctor, master, professors, senior engineers and other professional and technical personnel, our research and development centers base on Zhengzhou University and Xinxiang Medical Uniersity, include synthetic labs, 1 analysis lab and 2 pilot labs(Kilolab), it is equipped with Agilent 1200, HPLC, GC, LC, MS, KF-moisture tester and other high precision equipment.
We have three multi-functional fully equipped factories, one bio-fermentation workshop covering area of 40,000 square meters, and passed the ISO9001 certification, Reactor from 50L- 3000L, total capacity is 2000000L, providing quantity varies from kilogram to ton lots. We can also select the most shortcut route to approach the customer needs.
Our company devote ourselves the industrialization and promotion of biotechnology, strive to achieve the goal win-win among the company, employees, society, customers and suppliers, contribute to the cause of human health.
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Inquiry History8 Inquiries
Country Product Purchase Quantity Date Posted 
United States
CAS 987-78-0 Citicoline Cdp Choline
1 KG Oct 27, 2025 
India
Citicoline Base
500 KG Jun 27, 2025 
Mexico
Citicoline
1 KG Oct 15, 2025 
Poland
Citicoline Cdp Choline
50 KG Apr 29, 2024 
Vietnam
citicoline
1 KG Jun 29, 2026
United States
Citicoline
100 G Apr 10, 2026 
South Korea
Citicoline
500 KG Sep 3, 2026 
Bangladesh
Butyl Acetate
1.00 KG Nov 11, 2025 Post an enquiry for this product
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