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Home > Food Additives > Nutrition Supplements > Cytidine diphosphate choline for Sale > Cytidine 5'-diphosphocholine citicoline CDP coline
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Cytidine 5'-diphosphocholine citicoline CDP coline

TDS 8 Inquiries

Unit Price:

$100-120/KG FOB

Get Latest Price
CAS No.:

987-78-0

Grade:

Food Grade

Content:

99%

Port:

Shenzhen

Brand:

JaYoo

Packaging:

25kg per drum

Price valid (until):

2026-12-29

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Fisetin,Coenzyme PQQ,S-Acetyl L-Glutathione,D-Glucosamine Hydrochloride Powder Glucosamine Sulfate Potassium Chloride Powder,MSM Powder,Sodium Hyaluronate Powder

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


    What is Citicoline?  


    Citicoline is a choline precursor composed of cytidine and choline diphosphate, which helps maintain the membrane structure and signal transmission of nerve cells.CDP can promote the synthesis of phospholipids, improve the utilization of glucose and oxygen in the brain, expand brain microcirculation, and assist in improving age-related cognitive decline related discomfort. Widely used in brain health products.


    Product Name: Citicoline

    CAS number: 987-78-0

    Molecular formula: C14H26N4O11P2

    Molecular weight: 488.33

    EINECS number: 213-580-7

    Purity: > 98%

    Packaging specification: 25KG/drum

    Shop Cytidine 5'-diphosphocholine citicoline CDP coline-Detailed Image 1

    Test Items

    Specification

    Appearance

    White crystalline powder

    Purity

    ≥98%

    Identification

    (1)The solution should be positive


    (2)Retention time of major peak in the chromatogram of sample preparation should correspond to that of standard as obtained in assay by HPLC test


    1. The infrared absorption spectrum is

     concordant with the reference spectrum

    Solution

    Clear and colorless

    Chlorides

    ≤0.05%

    pH

    2.5 to 3.5

    Ammonium

    ≤0.05%

    Iron

    ≤ 0.01%

    Phosphate

    ≤ 0.1%

    Loss on drying

    4.0%

    5'-CMP

    ≤0.3%

    Other single impurity

    ≤ 0.2%

    Other total impurity

    ≤0.7%



    Mechanism of  Citicoline


    As a derivative of cytosine nucleoside, Citicoline participates in the biosynthesis of phospholipids in the body, promoting the metabolism and repair of damaged brain tissue phospholipids, improving the efficiency of glucose and oxygen uptake and utilization in the brain, improving brain energy metabolism, while inhibiting excessive release of excitatory amino acids in the brain, optimizing brain microcirculation, and repairing damaged neurons, improving brain cell dysfunction caused by cerebral ischemia and traumatic brain injury, and restoring nerve conduction function.


    Citicoline source and flow chart 


    Citicoline is mainly obtained by enzymatic reaction of cytidine to obtain crude Citicoline, which is then separated and purified to obtain high-purity CDP. Here is our product flowchart.

    Shop Cytidine 5'-diphosphocholine citicoline CDP coline-Detailed Image 2


    Main Efficacy


    1. Improving brain metabolism: promoting the synthesis of phospholipids in brain tissue, repairing nerve cells damaged by ischemia and trauma.
    2. Improve cognition and memory: alleviate forgetfulness and memory decline after brain injury, and assist in improving brain function decline in the elderly.


     What product could be used with Citicoline


    Citicoline can be combined with phosphatidylserine ( PS ) to synergistically repair brain cell membranes. Citicoline supplies choline to synthesize phospholipids, while PS stabilizes nerve cell membranes. Combined use improves forgetfulness, brain fatigue, and cognitive decline in middle-aged and elderly individuals.


      Where to buy CDP coline


    Do you want to purchase high-quality bulk powder of Citicoline? Welcome to choose us.As a  high-quality CDP manufacturer in China, we can provide stable and reliable CDP coline raw materials for industries such as health products,and food production. We have a highly competitive pricing system and can provide exclusive quotes based on your bulk orders, providing cost-effective solutions for enterprises of all sizes. Simultaneously supporting formula and packaging customization to meet your personalized production needs. With a well-established supply chain, we can efficiently deliver to global markets such as China, the United States, Europe, and India, with clear delivery cycles and timely and stable shipments. We are willing to become your trusted long-term partner for Citicoline powder. Welcome to call or write to discuss cooperation and place orders.

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    Certificates

    Basic Info
    Product Name:

    Cytidine diphosphate choline

    Other Name:

    Cytidine 5′-(trihydrogen diphosphate),P′-[2-(trimethylammonio)ethyl] ester,inner salt;Cytidine 5′-(trihydrogen diphosphate),P′-[2-(trimethylammonio)ethyl] ester,hydroxide,inner salt;Choline,hydroxide,5′-ester with cytidine 5′-(trihydrogen pyrophosphate),inner salt;Cytidine 5′-diphosphate choline;Citicoline;Cytidine diphosphate choline ester;Nicholin;Niticolin;Cereb;Colite;Nicolin;Recofnan;Ensign;Suncholin;CDP-choline;Cytidine diphosphate choline;Cytidine diphosphorylcholine;Cytidine diphosphocholine;Cytidine 5′-diphosphocholine;Cytidine 5′-(cholinyl pyrophosphate);Cytidine choline diphosphate;Cytidine 5′-(choline diphosphate);Choline 5′-cytidine diphosphate;Recognan;Choline cytidine diphosphate;Citicholine;Cytidoline;Citidoline;Somazina;Somazine;Reagin;Neucolis;Difosfocin;Sintoclar;Haocolin;Corenalin;Audes;Rexort;Citifar;Hornbest;Cyscholin;Emicholine F;NSC 122002;Cognizin;1477-47-0;64143-42-6;769081-33-6

    CAS No.:

    987-78-0

    Molecular Formula:

    C14H26N4O11P2

    InChIKeys:

    InChIKey=RZZPDXZPRHQOCG-OJAKKHQRSA-N

    Molecular Weight:

    488.32

    Exact Mass:

    488.107330

    EC Number:

    213-580-7

    DSSTox ID:

    DTXSID9048431

    NCI Thesaurus Code:

    C96743

    ATC Code:

    N - Nervous system

    HScode:

    2942000000

    Categories:

    Nutrition Supplements

    Characteristics
    PSA:

    214

    XLogP3:

    -7.07

    Appearance:

    Solid

    Boiling Point:

    851.4°C at 760 mmHg

    Toxicity:

    LD50 in mice, rats (mg/kg): 4600 ±335, 4150 ±370 i.v.; both species 8 g/kg orally (Grau)

    Specific rotation:

    D25 +19.0° (c = 0.86 in H2O)

    Collision Cross Section:

    197.6 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|200.64 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|198.86 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|208.98 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|208.41 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|198.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|207.8 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|205.9 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|210.2 Ų [M+Na-2H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|207.7 Ų [M-H]-

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Fisetin,Coenzyme PQQ,S-Acetyl L-Glutathione,D-Glucosamine Hydrochloride Powder Glucosamine Sulfate Potassium Chloride Powder,MSM Powder,Sodium Hyaluronate Powder

    Location:

    7C92B, Building 213, Tairan Science and Technology Park, No. 113 Tairan 4th Road, Tian'an Community, Shatou Subdistrict, Futian District, Shenzhen City

    Payment Terms:

    TT against copy of documents,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2025

    Shenzhen Jayoo Biotech Co., Ltd. is an emerging high-tech enterprise dedicated to the field of biological health. We are committed to delivering natural, safe, and highly effective health products and solutions to global markets.

    Our core strength lies in a professional team with over a decade of deep industry experience in the bio-health sector. Composed of seasoned R&D specialists and market-driven professionals, our team combines strong technical expertise with innovative thinking and commercial insight. In parallel, we have established preliminary collaborations with leading domestic universities and research institutions, leveraging their advanced scientific resources to accelerate product development and technology commercialization—injecting strong momentum into our long-term growth.

    Jayoo Biotech focuses on innovation in natural active ingredient extraction and biosynthesis technologies. Guided by our R&D philosophy of “Natural, Safe, and Effective,” we integrate modern biotechnology with advanced plant extraction processes to build differentiated technological advantages. Our product development spans multiple health-related sectors, including natural active ingredients, functional raw materials, and nutritional supplements, with continuous innovation driving enhanced product competitiveness.

  • Inquiry History
    8 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    CAS 987-78-0 Citicoline Cdp Choline

    1 KG Oct 27, 2025
    India

    Citicoline Base

    500 KG Jun 27, 2025
    Mexico

    Citicoline

    1 KG Oct 15, 2025
    Poland

    Citicoline Cdp Choline

    50 KG Apr 29, 2024
    Poland

    CITICOLINE, CYTIDINE 5'-DIPHOSPHOCHOLINE,CDP-Coline 98.0% white or almost white crystalline powder

    100 KG Sep 21, 2023
    Vietnam

    citicoline

    1 KG Jun 29, 2026
    United States

    Citicoline

    100 G Apr 10, 2026
    Bangladesh

    Butyl Acetate

    1.00 KG Nov 11, 2025
    Post an enquiry for this product
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