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Dabrafenib mesylate 1195768-06-9

Unit Price: Get Latest Price
CAS No.:

1195768-06-9

Grade:

Pharmaceutical Grade

Content:

99%

Brand:

Zison

Packaging:

foil bag

Price valid (until):

2023-03-31

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Avatrombopag,Lenvatinib,Safinamide mesylate,Axitinib

  • Product Description

  • Seller Information

  • Description


      Dabrafenib mesylate  


    Dabrafenib mesylate; N-{3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-2,6-difluorobenzenesulfonamide methanesulfonic acid

    ItemsSpecifications
    CAS1195768-06-9
    Storage conditionsHygroscopic, -20°C Freezer, Under inert atmosphere
    SolubilityDMSO (Slightly, Heated), Methanol (Slightly)

    Basic Info
    Product Name:

    Dabrafenib mesylate

    Other Name:

    Benzenesulfonamide,N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-,methanesulfonate (1:1);Dabrafenib mesylate;GSK 2118436 methanesulfonate salt;GSK 2118436B;N-[3-[5-(2-Aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide methanesulfonic acid

    CAS No.:

    1195768-06-9

    Molecular Formula:

    C23H20F3N5O2S2.CH4O3S

    InChIKeys:

    InChIKey=YKGMKSIHIVVYKY-UHFFFAOYSA-N

    Molecular Weight:

    615.6680696

    Exact Mass:

    615.089

    EC Number:

    1592732-453-0

    UNII:

    B6DC89I63E

    DSSTox ID:

    DTXSID70152500

    NCI Thesaurus Code:

    C128059

    ATC Code:

    L01EC02

    Categories:

    Inhibitor Drugs

    Characteristics
    PSA:

    210

    XLogP3:

    7.03360

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Serious eye damage, Category 1

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 2

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H315 Causes skin irritation

    H318 Causes serious eye damage

    H351 Suspected of causing cancer

    H361 Suspected of damaging fertility or the unborn child

    H373 May cause damage to organs through prolonged or repeated exposure

    H400 Very toxic to aquatic life

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Avatrombopag,Lenvatinib,Safinamide mesylate,Axitinib

    Location:

    Room 410, Building 9, No. 2566, Century Avenue, Jinan, 250104, China

    Payment Terms:

    TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $2.5 million-$5 million

    Total Employees:

    51-100

    Year of Establishment:

    2021

    Certifications:

    business license,ISO

    Zison Pharma,a leading manufacturer of APIs and pharma intermediates(Axitinib and intermediates, Avatrombopag and intermediates,Finerenone and intermediates,Lenvatinib and intermediates,Tenofovir alafenamide hemifumarate and intermediates,Safinamide and intermediates,Crizotinib and intermediates, Roxadustat and intermediates, Calcipotriene monohydrate and intermediates etc.)based in Jinan, China. With 10 years of experience in the APIs and pharma intermediates field, we understand that quality and service is the key to win in the fast-changing market and our client's success is our success,which is why in our customer relations we always put the needs of our clients first.
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