Eldecalcitol GMP DMF Ready 99%
GMP HALAL KOSHER ISO FDA
104121-92-8
Pharmaceutical Grade
99%
any port of China
25Kg/Drum;1Kg/Bottle
Yes
2023-09-03
APIs,Veterinary,Cosmetic Ingredients,Peptides,intermediates,food ingredients
-
Product Description
-
Seller Information
-
DescriptionECHEMI Editorial ReferenceEldecalcitol (Edirol) was approved in January 2011 by the Japanese Ministry of Health, Labor, and Welfare for the treatment of osteoporosis. Because of vitamin D’s central role in the bone health, vitamin D and analogs of vitamin D have been used to treat patients diagnosed with osteoporosis. Eldecalcitol is an analog of the active form of vitamin D, calcitriol, in which the lower cyclohexane ring contains a hydroxypropyl group. The synthesis of eldecalcitol involves the assembly of two units, a fully protected (3S,4S,5R)-oct-1-en-7-yne-3,4,5-triol and a fused bicyclic system, (R)-6- ((1R,3aR,7aR,E)-4-(bromomethylene)-7a-methyloctahydro-1H-inden-1- yl)-2-methylheptan-2-ol, through a Diels-Alder reaction to give fully protected eldecalcitol. The hydroxyl groups are then deprotected to give the parent molecule. Eldecalcitol binds to the vitaminDreceptor 2.7-fold more potently than calcitriol, while only weakly inhibiting serum parathyroid hormone.
ChEBI: A hydroxycalciol that is calcitriol with a 3-hydroxypropoxy group at position 2.CertificatesBasic Info-
Product Name:
2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
Other Name:2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3;Eldecalcitol;ED-71;(1R,Z)-5-((E)-2-((1R,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol;1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3;Eldecalcitol(ED-71);2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitaMin D3;(1S,2S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol
CAS No.:104121-92-8
Molecular Formula:C30H50O5
InChIKeys:FZEXGDDBXLBRTD-AYIMTCTASA-N
Molecular Weight:490.71
EC Number:686-849-3
Color/Form:White to off-white
Categories:
Characteristics-
Density:
1.10
Melting Point:126-128℃
Boiling Point:655.7±55.0 °C(Predicted)
PKA:13.80±0.60(Predicted)
Critical Temperature & Pressure:Store at -20°C
-
-
Seller Information
-
Business Type:
Manufactory
-
Main Products:
APIs,Veterinary,Cosmetic Ingredients,Peptides,intermediates,food ingredients
-
Location:
T2-805,European and American Financial City,Cangqian Street,Yuhang District,Hangzhou,China.(zip code:311121)
-
Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance
-
Average lead Time:
20 days
-
Total Annual Revenue:
$10 million-$25 million
-
Total Employees:
11-50
-
Year of Establishment:
2009
-
-
Country Product Purchase Quantity Date Posted Post an enquiry for this product
More from this Seller
-
-
![Apalutamide GMP 99% White to Light Yellow Holy Pharm]( "Apalutamide GMP 99% White to Light Yellow Holy Pharm")
-
Apalutamide GMP 99% White to Light Yellow Holy Pharm
Pharmaceutical Grade / 99%
-
-
-
![Resveratrol]( "Resveratrol")
-
Resveratrol
Cosmetics Grade
-
-
-
![Glutaric acid]( "Glutaric acid")
-
Glutaric acid
Industrial Grade / 99%
-
-
-
![Josamycin GMP 99% White to Light Yellow Holypharm]( "Josamycin GMP 99% White to Light Yellow Holypharm")
-
Josamycin GMP 99% White to Light Yellow Holypharm
Pharmaceutical Grade / 99%
-
-
-
![Collagen III 99% white ctystalline powder]( "Collagen III 99% white ctystalline powder")
-
Collagen III 99% white ctystalline powder
Pharmaceutical Grade / 99%
-
-
-
![(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid]( "(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid")
-
(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
Industrial Grade / 98%
-
