Eldecalcitol cas 104121-92-8
104121-92-8
Pharmaceutical Grade
99%
qingdao
25kg/Cardboard Drum
2026-10-26
API,Antibiotics,Anti cancer category
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceEldecalcitol (Edirol) was approved in January 2011 by the Japanese Ministry of Health, Labor, and Welfare for the treatment of osteoporosis. Because of vitamin D’s central role in the bone health, vitamin D and analogs of vitamin D have been used to treat patients diagnosed with osteoporosis. Eldecalcitol is an analog of the active form of vitamin D, calcitriol, in which the lower cyclohexane ring contains a hydroxypropyl group. The synthesis of eldecalcitol involves the assembly of two units, a fully protected (3S,4S,5R)-oct-1-en-7-yne-3,4,5-triol and a fused bicyclic system, (R)-6- ((1R,3aR,7aR,E)-4-(bromomethylene)-7a-methyloctahydro-1H-inden-1- yl)-2-methylheptan-2-ol, through a Diels-Alder reaction to give fully protected eldecalcitol. The hydroxyl groups are then deprotected to give the parent molecule. Eldecalcitol binds to the vitaminDreceptor 2.7-fold more potently than calcitriol, while only weakly inhibiting serum parathyroid hormone.
ChEBI: A hydroxycalciol that is calcitriol with a 3-hydroxypropoxy group at position 2.Basic Info-
Product Name:
2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3
Other Name:2-(3-hydroxypropoxy)-1,25-dihydroxyvitamin D3;Eldecalcitol;ED-71;(1R,Z)-5-((E)-2-((1R,7aR)-1-((R)-6-hydroxy-6-methylheptan-2-yl)-7a-methylhexahydro-1H-inden-4(2H)-ylidene)ethylidene)-2-(3-hydroxypropoxy)-4-methylenecyclohexane-1,3-diol;1alpha,25-dihydroxy-2beta-(3-hydroxypropoxy)vitamin D3;Eldecalcitol(ED-71);2.beta.-(3-Hydroxypropoxy)-1.alpha.,25-dihydroxyvitaMin D3;(1S,2S,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-2-(3-hydroxypropoxy)-4-methylidenecyclohexane-1,3-diol
CAS No.:104121-92-8
Molecular Formula:C30H50O5
InChIKeys:FZEXGDDBXLBRTD-AYIMTCTASA-N
Molecular Weight:490.71
EC Number:686-849-3
Color/Form:White to off-white
Categories:
Characteristics-
Density:
1.10
Melting Point:126-128℃
Boiling Point:655.7±55.0 °C(Predicted)
PKA:13.80±0.60(Predicted)
Critical Temperature & Pressure:Store at -20°C
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Seller Information
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Business Type:
Trader
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Main Products:
API,Antibiotics,Anti cancer category
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Location:
12A02-9, Union Building, Building 1, No. 216 Tongchuan Road, Licang District, Qingdao City, Shandong Province
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15
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Total Annual Revenue:
$25 million-$50 million
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Total Employees:
201-300
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Year of Establishment:
2024
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Certifications:
Hazardous Chemicals Business License,Supplier Agreement
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