Bosutinib Monohydrate 99% see COA Kanbei kanbei
GMP ISO 1 Inquiries
918639-08-4
Industrial Grade
99%
qingdao
kanbei
25kg drum
2022-07-18
PVC resin,pvc paste resin,melamine
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceBosutinib hydrate is a hydrate that is the monohydrate form of anhydrous bosutinib. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains a bosutinib.|Bosutinib Monohydrate is the monohydrate form of bosutinib, a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl and Src kinases with potential antineoplastic activity. Unlike imatinib, bosutinib inhibits the autophosphorylation of both Abl and Src kinases, resulting in inhibition of cell growth and apoptosis. Because of the dual mechanism of action, this agent may have activity in resistant CML disease, other myeloid malignancies and solid tumors. Abl kinase is upregulated in the presence of the abnormal Bcr-abl fusion protein which is commonly associated with chronic myeloid leukemia (CML). Overexpression of specific Src kinases is also associated with the imatinib-resistant CML phenotype.CertificatesBasic Info
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Product Name:
Bosutinib monohydrate
Other Name:3-Quinolinecarbonitrile,4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-,hydrate (1:1);Bosutinib monohydrate
CAS No.:918639-08-4
Molecular Formula:C26H29Cl2N5O3.H2O
InChIKeys:InChIKey=BXPOSPOKHGNMEP-UHFFFAOYSA-N
Molecular Weight:548.5
Exact Mass:547.1753099
UNII:844ZJE6I55
DSSTox ID:DTXSID20238722
NCI Thesaurus Code:C154440
ATC Code:L01XE14
Categories:
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Seller Information
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Business Type:
Trader
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Main Products:
PVC resin,pvc paste resin,melamine
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Location:
Room 405, Unit 2, Building 1, Taiji Mansion, No. 38, Nanyang Road, Jinshui District, Zhengzhou City, Henan Province
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
90
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
Pakistan
Bosutinib Monohydrate
1 KG Jun 24, 2025 Post an enquiry for this product