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L-Tryptophan | CAS 73-22-3 | Essential Amino Acid for Animal Feed, Food and Pharmaceutical Use

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Unit Price:

$5-6/KG EXW

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CAS No.:

73-22-3

Grade:

Feed Grade

Content:

98%

Port:

qingdao

Packaging:

20kgs/bag

Sample Available:

Yes

Price valid (until):

2027-03-11

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PREMIUM INGREDIENT CO.,LTD

Company Type:

Manufactory

Location:

United Kingdom

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

80 days

Qualification:

Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

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Product Details
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Description

Product Detail

Basic Information

L-Tryptophan
Synonym	L-Tryptophane, (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid
CAS No.	73-22-3
Molecular Formula	C₁₁H₁₂N₂O₂
Molecular Weight	204.23
Appearance	White or off-white crystalline powder
Assay	98.5% – 101.5%
Available Grade	Feed Grade, Food Grade, Pharmaceutical Grade
Executive Standard	USP, AJI, FCC, Feed Special Standard
Certifications	ISO9001, HALAL, KOSHER, FAMI-QS, Non-GMO

Product Overview

L-Tryptophan (Cas No.: 73-22-3) is an essential aromatic amino acid produced by microbial fermentation, presented as white or off-white crystalline powder. As an indispensable nutrient substance that cannot be synthesized by living organisms, it is widely used as a key nutritional fortifier. It serves as an important amino acid additive for animal feed formulation, and is also applied in functional food and dietary supplement production for body nutrition regulation. Additionally, it can be used as a raw material for pharmaceutical intermediate preparation.

Character

L-Tryptophan is a stable aromatic essential amino acid with indole ring structure. It is slightly soluble in water and maintains stable physical and chemical properties under cool, dry and sealed storage environments. Adopting advanced microbial fermentation technology, the product features high purity, low impurities and stable batch quality.

It is a critical limiting amino acid for animal nutrition and an important nutritional amino acid for human body metabolism. It acts as a synthetic precursor of serotonin and melatonin, participating in multiple physiological regulation processes. The product adapts to industrial production requirements of feed fortification, food nutrition supplementation and fine pharmaceutical processing.

Main Functions

1. Optimize Animal Feed Nutrition

L-Tryptophan is a vital limiting amino acid for livestock and poultry breeding. Conventional plant-based feed materials are commonly deficient in tryptophan. Reasonable supplementation of L-Tryptophan can balance the overall amino acid structure of feed formulas, make up for nutritional deficiencies in daily feed, and greatly improve feed digestibility and utilization efficiency.

It effectively promotes the growth and development of livestock, poultry and aquatic animals, increases daily weight gain, and improves animal feeding status and survival rate. Meanwhile, it can reduce the addition proportion of high-protein raw materials in feed, lower feeding cost, and optimize the scientific collocation of low-protein feed formulas, which is an essential additive in modern precision breeding industry.

2. Human Body Nutritional Regulation & Fortification

As an essential amino acid for human body, L-Tryptophan participates in human protein synthesis and metabolic regulation. It is the core precursor substance for synthesizing serotonin and melatonin in the human body, helping maintain normal nervous system function and healthy sleep state. It is widely used in compound amino acid nutrition formulas to supplement daily dietary amino acid deficiency.

3. Pharmaceutical Raw Material Application

L-Tryptophan can be used as a basic raw material for pharmaceutical amino acid preparations and biological intermediates, applied in fine pharmaceutical production.

Applications

1. Animal Feed Industry

This is the primary application field of L-Tryptophan. It is widely added in feed for pigs, poultry, ruminants and aquatic products. It improves the amino acid balance of feed, solves the problem of insufficient natural tryptophan in plant feed, enhances feed conversion efficiency, promotes animal growth and improves breeding economic benefits. It is suitable for large-scale industrial feed production and low-protein feed formula optimization.

2. Functional Food & Dietary Supplements

L-Tryptophan is used for nutritional fortification of functional food, health care products and compound amino acid supplements. It is applied in nutritional powder, functional beverage and customized dietary formula products to supplement essential amino acids and assist physical state regulation.

3. Pharmaceutical Industry

Applied in the preparation of amino acid infusion, health pharmaceutical intermediates and related biological fine chemical products for medical nutritional supplementation.

Packaging & Storage

Packaging: 25kg kraft paper bag with inner PE plastic bag, customized packaging is acceptable.

Storage: Store in cool, dry, ventilated warehouse, keep tightly sealed, avoid high temperature, direct sunlight and damp environment.

Shelf Life: 24 months under standard storage conditions.

Item	specification
Appearance	White to light yellow crystal powder
Assay %	≥98.50
Specific Rotation	-29.0° -32.8°
Residue on Ignition/%	≤0.50
Loss on Drying/%	≤0.50
Heavy Metal(Pb)/%	≤0.0020
Arsenic(As)/%	≤0.0002
Mercury(Hg)/%	≤0.00001
Cadmium(Cd)/%	≤0.0002
Salmonella	Negative in 10g
PH	5.0~7.0

ECHEMI Editorial Reference

L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3[1].
L-tryptophan is a white powder with a flat taste. An essential amino acid; occurs in isomeric forms. (NTP, 1992)|Solid
L-tryptophan is a white powder with a flat taste. An essential amino acid; occurs in isomeric forms. (NTP, 1992)|L-tryptophan is the L-enantiomer of tryptophan. It has a role as an antidepressant, a nutraceutical, a micronutrient, a plant metabolite, a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is an erythrose 4-phosphate/phosphoenolpyruvate family amino acid, a proteinogenic amino acid, a tryptophan and a L-alpha-amino acid. It is a conjugate base of a L-tryptophanium. It is a conjugate acid of a L-tryptophanate. It is an enantiomer of a D-tryptophan. It is a tautomer of a L-tryptophan zwitterion.|An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.|Tryptophan is the least plentiful of all 22 amino acids and an essential amino acid in humans (provided by food), Tryptophan is found in most proteins and a precursor of serotonin. Tryptophan is converted to 5-hydroxy-tryptophan (5-HTP), converted in turn to serotonin, a neurotransmitter essential in regulating appetite, sleep, mood, and pain. Tryptophan is a natural sedative and present in dairy products, meats, brown rice, fish, and soybeans. (NCI04)|An essential amino acid that is necessary for normal growth in infants and for NITROGEN balance in adults. It is a precursor of INDOLE ALKALOIDS in plants. It is a precursor of SEROTONIN (hence its use as an antidepressant and sleep aid). It can be a precursor to NIACIN, albeit inefficiently, in mammals.

Certificates

Basic Info

Product Name:

L-Tryptophan

Other Name:

L-Tryptophan;Tryptophan,L-;l-β-3-Indolylalanine;Tryptophane;Tryptophan;L-Tryptophane;1H-Indole-3-propanoic acid,α-amino-,(S)-;L-(-)-Tryptophan;l-α-Aminoindole-3-propionic acid;2-Amino-3-indolylpropanoic acid;(S)-α-Aminoindole-3-propionic acid;(-)-Tryptophan;1H-Indole-3-alanine,(S)-;EH 121;(S)-Tryptophan;(S)-α-Amino-1H-indole-3-propanoic acid;(S)-α-Amino-β-indolepropionic acid;3-Indol-3-ylalanine;L-Alanine,3-(1H-indol-3-yl)-;Lyphan;NSC 13119;(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-Amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-Azaniumyl-3-(1H-indol-3-yl)propanoate;6912-86-3;80206-30-0;154635-35-5;2416148-24-6

CAS No.:

73-22-3

Molecular Formula:

C11H12N2O2

InChIKeys:

InChIKey=QIVBCDIJIAJPQS-VIFPVBQESA-N

Molecular Weight:

204.22500

Exact Mass:

204.23

EC Number:

200-795-6

UNII:

8DUH1N11BX

NSC Number:

757373

DSSTox ID:

DTXSID5021419

NCI Thesaurus Code:

C29603

Color/Form:

Leaflets or plates from dilute alcohol|White to slightly yellowish-white ... crystals or crystalline powder

ATC Code:

N - Nervous system

HScode:

2933990090

Categories:

Amino Acids and Derivatives

Characteristics

PSA:

79.11000

XLogP3:

-1.1

Appearance:

L-tryptophan is a white powder with a flat taste. An essential amino acid; occurs in isomeric forms. (NTP, 1992)

Density:

1.4±0.1 g/cm3

Melting Point:

282 °C

Boiling Point:

447.9°C at 760 mmHg

Flash Point:

224.7±25.9 °C

Refractive Index:

1.698

Water Solubility:

H2O: 13.4 mg/mL at 25 °C

Storage Conditions:

Protect from light

Vapor Pressure:

2.1X10-9 mm Hg at 25 deg C (est)

Toxicity:

LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000).

Specific rotation:

Specific optical rotation: -31.5 deg at 23 °C/D (water, 1%), +2.4 deg at 20 °C/D (hydrochloric acid, 0.5 N); +0.15 deg at 20 °C/D (sodium hydroxide, 2.43% in 0.5 N)

Odor:

Odorless

Taste:

FLAT TASTE

PH:

A 1% solution in water has a pH of 5.5 to 7.

PKA:

7.38(at 25 °C)

Dissociation Constants:

7.38 (at 25 °C)|pK1 = 2.38 /SRC: carboxylic acid/; pK2 = 9.39 /SRC: primary amine/

Collision Cross Section:

154.22 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|158.58 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|145 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|150.1 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|150.3 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|147.6 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|147.7 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|142.3 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|142.5 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|151.5 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|149.1 Å² [M-H]-

Experimental Properties:

Decomposes at 289 °C (rapid heating)|Needles from methanol, decomposes at 251 °C /Tryptophan hydrochloride/|UV: 3453 (Sadtler Research Laboratories Spectral Collection) /Tryptophan (DL)/

Air and Water Reactions:

Slightly soluble in water.

Reactive Group:

Salts, Acidic

Reactivity Profile:

Acidic salts, such as L-TRYPTOPHAN, are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

See More L-Tryptophan Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Protect from light

See More L-Tryptophan Safety Data Sheet 

Seller Information

Business Type: Manufactory
Main Products: l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate
Location: dongsheng road
Payment Terms: TT against copy of documents,L/C
Average lead Time: 80 days
Total Annual Revenue: $5 million-$10 million
Total Employees: 5-10
Year of Establishment: 2015

Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade.

Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents.

Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.

We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.

◆Amino Acids	◆ phosphates	◆ acidulants
◆ preservatives	◆ sweeteners	◆ functional fiber&bulking agent
◆ thickeners	◆ Leavening agents	◆ mineral products
◆ Botanical extracts	◆ vitamins	◆ nutritional products

Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.

Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.

------------------------------------- Mission------------------------------------

Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.

-------------------------------------Our Quality------------------------------------

Our Quality

As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

Strict Supplier Due‑Diligence

Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

Batch‑by‑batch Document Verification

For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

Independent Third‑party Testing Coordination

Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

Quality Closure & Continuous Improvement

We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:

★ ISO Certification ★ Halal Certificate

★ Kosher Certificate ★ IP certificate

★ Haccp certificate ★ Allergens with Glutens

★ GRAS Statement ★ HACCP Program

★ BSE/TSE Statement ★ Certificate of Analysis

★ Country of Origin Certificate ★ Material Safety Data Sheet

★ Flow Chart (product processing) ★ Food Grade Certificate

★ Nutritional Information ★ GMO Statement

★ Specification Sheet

Inquiry History

28 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	L-Tryptophan (Vegan Only)	50.00 KG	Mar 24, 2026
India	L-Tryptophan powder	25.00 KG	Feb 13, 2025
Peru	L-Tryptophan	3000 KG	Sep 20, 2026
India	L Tryptophan	25.00 KG	Oct 30, 2025
United States	L-Tryptophan	1 MT	Apr 16, 2025
Egypt	L-Tryptophan	1000 KG	Jun 27, 2024
India	L- Tryptophan 98.5%	5.00 MT	Oct 16, 2025
Egypt	L-Tryptophan powder	100.00 KG	Oct 11, 2025
Greece	TRYPTOPHAN (Trp, W)	300.00 KG	Sep 25, 2025
India	L Tyrptophan	1.00 KG	Apr 25, 2025
United Kingdom	L-Tryptophan powder	15.00 MT	Nov 22, 2024
United States	L-Tryptophan Powder	10 MT	Oct 18, 2024
Russia	L-Tryptophan	25 KG	Sep 24, 2024
Slovenia	L-TRYPTOPHAN	400 G	Jan 9, 2026
India	L-Tryptophan	1 MT	Apr 23, 2025
United Kingdom	L-Tryptophan powder	1.00 20' Fcl	Apr 2, 2025
India	Sodium Hydroxide	100.00 KG	Feb 13, 2025
India	L-Tyrosine	25.00 KG	Feb 13, 2025
India	Acetic acid/GAA	1.00 20' Fcl	Feb 26, 2024
United Kingdom	L-Lysine MonoHCL	50.00 KG	Jun 12, 2025

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