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Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss buy - large image1

Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss buy - image1

Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss buy - image2

Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss

Name: Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss
Brand: HANDOM CHEM
SKU: pr2305171559
Price: 85 USD
Availability: InStock

TDS 326 Inquiries

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Content:

95%

Port:

Shanghai, Beijing, Guangzhou or Dalian

Brand:

HANDOM CHEM

Packaging:

1g/bottle, 5g/bottle or according to the requirements from customers.

Sample Available:

Yes

Price valid (until):

2024-12-31

Contact Supplier

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Details

Product Name: Semaglutide

CAS No.: 910463-68-2

EINECS No.: 203-405-2

Molecular Formula: C187H291N45O59

Molecular Weight: 4113.58

Sequence: His-Aib-Glu-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-N6-[N-(17-carboxy-1-oxoheptadecyl-L-γ-glutamyl[2-(2-aminoethoxy]acetyl[2-2-aminoethoxy)ethoxy]acetyl]-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH

Shop Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss-Detailed Image 1

Test Items	Specifications
Appearance	White or almost white loose powder
Solubility	Freely soluble in water; Firstly, to add freshly boiled and cooled water to make a clear solution containing 0.15mg of semaglutide in 1ml. Then, to adjust the pH of the solution to 5.5 with 0.05M hydrochloric acid and keep for 30 seconds. Finally, to adjust the pH of the solution to 3.0 and keep 30 seconds. The solution should be turbid in the range of pH 3.0 to 5.5.
Specific optical rotation[α]20D	-15.0° to -10.0°(anhydrous and sodium ion-free substance, C=10mg/ml, H2O)
Identification by HPLC	The retention time of the principal peak of the test solution corresponds to that of the reference solution, as obtained in the assay.
Molecular Ion Mass by MS	4113.58 ± 1.0
Amino acid content	Asp: 0.9 ~ 1.1
	Ser: 2.7 ~ 3.3
	Glu: 4.5 ~ 5.5
	Gly: 3.6 ~ 4.4
	His: 0.9 ~ 1.1
	Arg: 1.8 ~ 2.2
	Thr: 1.8 ~ 2.2
	Ala: 2.7 ~ 3.3
	Aib: 0.9 ~ 1.1
	Tyr: 0.9 ~ 1.1
	Val: 1.8 ~ 2.2
	Lys: 0.9 ~ 1.1
	Ile: 0.9 ~ 1.1
	Leu: 1.8 ~ 2.2
	Phe: 1.8 ~ 2.2
	AEEA: Should be detected
Peptide Map	The peptide map of the test solution corresponds to that of the reference solution, as obtained in the assay
Specific Activity	70% ~ 150%
pH Value	7.0 ~ 9.0
Water Content (K. F)	Not more than 8.0%
The clarity and colour of the solution	Clear and colourless
Purity (HPLC)	Not less than 95.0%
Related Substances (HPLC)	Total impurities: ≤5.0%
High Molecular Protein	Not more than 0.50%
Residual Solvents	Acetonitrile: ≤410 ppm
Residual Solvents	Isopropyl ether: ≤5000 ppm
Bacterial Endotoxins	Not more than 10 EU/mg
Host Cell Protein	Not more than 0.01%
Host Cell DNA	Not more than 10.0 ng/mg
Microbial Limits	Total Aerobic Microbial Count: ≤200 CFU/g
Microbial Limits	Total combined Yeasts & Mould Count: ≤100 CFU/g
Acid Group Ions	Trifluoroacetate Ion: ≤0.10%
	Phosphate Ion: ≤0.10%
	Acetate Ion: ≤0.10%
Peptide Content	Not less than 85.0%
Particle Size Distribution	90% particles(d90): ＜50 μm

Applications:

Semaglutide is a diabetes medicine used to treat adults with poorly controlled type 2 diabetes through diet and exercise. It is a glucagon-like peptide 1 (GLP-1) receptor agonist, which can mimic its effects, reduce hunger, reduce food intake, and reduce calorie intake, so it is also very effective in weight loss.

Packaging:

1g/bottle, 5g/bottle, 10g/bottle or according to the specific requirements from customers.

Storage Conditions:

Preserved in unopened original containers at a temperature of -20±5℃; kept away from direct sunlight, heat and moisture.

Shelf Life:

36 months if stored under above conditions.

ECHEMI Editorial Reference

Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

Certificates

Basic Info

Product Name:

Semaglutide

Other Name:

Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

EC Number:

203-405-2

Color/Form:

White to off-white

Categories:

Polypeptide

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

Critical Temperature & Pressure:

Store at -20°C

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

326 Inquiries

Country	Product	Purchase Quantity	Date Posted
United Kingdom	TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2	50 MT	Nov 13, 2023
United States	10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide	10 MT	Oct 18, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10 MT	Sep 19, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	2	Nov 13, 2024
United States	semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery	1 MT	Nov 4, 2023
Singapore	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	2 G	Nov 3, 2023
United States	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	100 MT	Oct 26, 2023
India	Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2	100	Nov 8, 2023
United States	99.9% Purity Semaglutide Petide 910463-68-2 For Type II diabetes mellitus Obesity	50 MT	Nov 11, 2023
United States	GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2	1 MT	Oct 25, 2023
United Kingdom	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	10	Oct 19, 2023
Canada	Semaglutide	1 G	Jun 24, 2024
United States	Semaglutide	5 MG	May 29, 2024
United States	semaglutide	30 MG	Mar 25, 2026
New Zealand	Semaglutide	1 G	Mar 18, 2026
Vietnam	semaglutide powder	10 G	Sep 26, 2024
India	Semaglutide	1.00 KG	Oct 8, 2024
India	Semaglutide	1 KG	Sep 29, 2024
Germany	Semaglutide	1 G	Oct 14, 2026
United States	Semaglutide	10 MT	Sep 25, 2026

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Semaglutide 95.0%~105.0% for type 2 diabetes and effective weight loss

Product Description

Seller Information