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ABT 263 Navitoclax 99% white powder 923564-51-6 Senwayer

Name: ABT 263 Navitoclax 99% white powder 923564-51-6 Senwayer
Brand: Senwayer
SKU: pr2305301423
Price: 280 USD
Availability: InStock

TDS 2 Inquiries

Unit Price: Get Latest Price 

CAS No.:

923564-51-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Senwayer

Packaging:

bag

Price valid (until):

2023-05-12

Contact Supplier

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Dingwang Technology (Wuhan) Co., Ltd.

Company Type:

Trader

Location:

China

Qualification:

Main Products:

API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

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Product Description
Seller Information
Inquiry History

Description

Product Introduction

ABT-263 (Navitoclax) is a potent and orally bioavailable Bcl-2 family inhibitor. This small molecule mimetic of BH3 domains specifically binds to Bcl-2, Bcl-xL, and Bcl-W with a Kivalue of less than 1 nM (1). ABT-263 (Navitoclax) has been shown to have antitumor effects on small cell lung cancer (SCLC) xenograft models, resulting in complete tumor regression in some cases (2). Studies have shown that ABT-263 (Navitoclax) can enhance the effectiveness of chemotherapeutic and targeted agents against solid tumors (3). ABT-263 (Navitoclax) induces apoptosis, particularly in certain types of senescent cells (4,5).

Product name	ABT 263
CAS No.	923564-51-6
MF	C47H55ClF3N5O6S3
MW	974.61
Melting point	114-116°C
EINECS No.	N/A
Boiling point	N/A
Density	1.41±0.1 g/cm3(Predicted)
Storage	-20°C Freezer, Under Inert Atmosphere
Solubility	Soluble in DMSO (up to 25 mg/ml).

About us

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.

We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.

With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

If you are interested, pls contact me freely!

Certificates

Basic Info

Product Name:

ABT 263

Other Name:

Benzamide,4-[4-[[2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]-;4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;ABT 263;Navitoclax;A 855071.0;1000696-69-4

CAS No.:

923564-51-6

Molecular Formula:

C47H55ClF3N5O6S3

InChIKeys:

InChIKey=JLYAXFNOILIKPP-KXQOOQHDSA-N

Molecular Weight:

974.61

Exact Mass:

974.61

HScode:

29339900

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

170

XLogP3:

9.6

Appearance:

pale yellow solid

Density:

1.4±0.1 g/cm3

Melting Point:

114-116°C

Refractive Index:

1.655

Storage Conditions:

-20°C Freezer, Under Inert Atmosphere

See More ABT 263 Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More ABT 263 Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
API,nutrition supplements,plant extract,peptide,HCG,6-Aminocaproic acid

Location:
Room 707, Block A, Zhongxing Times Digital Trade Port, No. 79 Xudong Street, Hongshan District, Wuhan City

Payment Terms:
TT against copy of documents,L/C

Average lead Time:
10

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
51-100

Year of Establishment:
2020

Certifications:
Verified supplier certificate,SGS

Dingwang Technology (Wuhan) Co., Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Peptide, Nutritional supplements,food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises.
We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places.
Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement.
We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc.
With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	ABT 263 Navitoclax 99% white powder 923564-51-6 Senwayer	2 G	Jun 26, 2023
United States	ABT 263; Navitoclax	1 G	Feb 26, 2026

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