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Liraglutide 95.0%~105.0% White or almost white loose powder HANDOM CHEM

Name: Liraglutide 95.0%~105.0% White or almost white loose powder HANDOM CHEM
Brand: HANDOM CHEM
SKU: pr2306091334
Price: 700 USD
Availability: InStock

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CAS No.:

204656-20-2

Grade:

Pharmaceutical Grade

Content:

95%

Port:

Beijing, Dalian, Shanghai or Guangzhou

Brand:

HANDOM CHEM

Packaging:

1g/bottle, 5g/bottle

Sample Available:

Yes

Price valid (until):

2023-08-31

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Details

Product Name: Liraglutide

CAS No.: 204656-20-2

Molecular Formula: C172H265N43O51

Molecular Weight: 3751.2

Liraglutide is a human glucagon-like peptide-1 (GLP-1) analogue indicated for the control of blood sugar in adults with type Ⅱ diabetes.

Test Items	Specifications
Appearance	White or almost white loose powder
Solubility	Freely soluble in water, soluble in methanol, very slightly soluble in ethanol
Hygroscopicity	Hygroscopic
Specific optical rotation	-15.0°to -30.0°(on the anhydrous and sodium ion-free substance, c=10mg/ml in water at 25℃)
Identification(By HPLC)	The retention time of Liraglutide peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
Molecular Ion Mass	3751.29
Amino acid Content	Asp: 0.9 ~ 1.1
	Glu: 4.5 ~ 5.5
	Ser: 2.7 ~ 3.3
	Gly: 3.6 ~ 4.4
	His: 0.9 ~ 1.1
	Arg: 1.8 ~ 2.2
	Thr: 1.8 ~ 2.2
	Ala: 3.6 ~ 4.4
	Aib: 0.9 ~ 1.1
	Tyr: 0.9 ~ 1.1
	Val: 1.8 ~ 2.2
	Lys: 0.9 ~ 1.1
	Ile: 0.9 ~ 1.1
	Leu: 1.8 ~ 2.2
	Phe: 1.8 ~ 2.2
pH Value	8.7 ~ 9.5
Water Content(K. F)	Not more than 8.0%
The clarity and colour of the solution	Clear and colourless
Related Substances(HPLC)	Maximum single impurity: ≤1.0%
Related Substances(HPLC)	Total impurities: ≤2.0%
High molecular protein	Not more than 0.5%
Residual Solvents Ⅰ	Methylene Chloride: ≤600ppm
	Acetonitrile: ≤410ppm
	Methanol: ≤3000ppm
	Isopropyl ether: ≤5000ppm
Residual Solvents Ⅱ	N,N-Dimethylformamide: ≤880ppm
Bacterial Endotoxins	Not more than 10EU/mg
Microbial Limits	TAMC: ≤200CFU/g
Microbial Limits	TYMC: ≤100CFU/g
Sodium ion	2.0% ~ 4.0%
Acid Group Ions	Trifluoroacetate ion(TFA): ≤0.1%
Acid Group Ions	Chloride ion: ≤0.1%
Assay(C172H265N43O51)	95.0% ~ 105.0% (Calculated with reference to the anhydrous and sodium ion-free substance.)

Packaging:
1g/bottle, 5g/bottle or according to the specific requirements from customers.

Storage Conditions:
Preserved in unopened original containers in a cool dry place before using; kept away from direct sunlight, heat and moisture.

Shelf Life:
24 months after manufacturing date if stored under above mentioned conditions.

ECHEMI Editorial Reference

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.
Liraglutide is characterized as a white to almost white powder. It is freely soluble in aqueous base solutions (> 270 mg/mL), but its water solubility decreases below pH 7 and reaches its lowest level at pH 4-5 (approximately 0.05 mg/mL). Solubility increases marginally at pH 2.5 where it is very slightly soluble (≤ 0.8 mg/mL). Liraglutide is soluble in methanol (68 mg/mL) and very slightly soluble in ethanol (1.1 mg/mL). The isoelectric point of liraglutide is approximately 4.9. The pH of a 1 mg/mL aqueous solution of drug substance is approximately 9.3.
ChEBI: Liraglutide, a lipopeptide and polypeptide, is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. It is used alongside diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Liraglutide functions as a glucagon-like peptide-1 receptor agonist and serves as a neuroprotective agent.
Liraglutide is GLP-1(1–37) modified at Ly: the -amino group is acylated with an (N-hexadecanoyl)glutam- -yl moiety that noncovalently but avidly binds tohuman serum albumin. (Also, Lys is conservatively replacedwith Arg.) These changes provide for a greatly extendedserum t12 of～10 to 15 hours after sc administration(0.6–1.8 mg), allowing for once-daily dosing.Liraglutide (Victoza, Novo Nordisk) is awaiting approvalby the FDA, EMEA, and the Koˉ roˉ -shoˉ (Japan).
Liraglutide peptide is a single, non-glycosylated polypeptide chain containing 31 amino acids, having a molecular mass of 3751 Dalton and a Molecular formula of C172H265N43O51.

Basic Info

Product Name:

Liraglutide

Other Name:

Liraglutide;Glycine, L-histidyl-L-alanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamylglycyl-L-glutaminyl-L-alanyl-L-alanyl-N6-(N-(1-oxohexadecyl)-L-gamma-glutamyl)-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-arginylglycyl-L-arginyl-;Liraglutida;Liraglutida [inn-spanish];Liraglutide [usan:inn];Liraglutidum;Liraglutidum [inn-latin];N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)glp-1-(7-37)-peptide

CAS No.:

204656-20-2

Molecular Formula:

C172H265N43O51

InChIKeys:

YSDQQAXHVYUZIW-VTFFJMQZNA-N

Molecular Weight:

3751.202

Exact Mass:

3748.95000

EC Number:

810-818-7

Color/Form:

White to Off-White

Categories:

Polypeptide

Characteristics

PSA:

1513.76000

XLogP3:

6.12960

Melting Point:

>182°C (dec.)

Critical Temperature & Pressure:

Refrigerator

Research

Class:

GLP-1 receptor agonist (acylated GLP-1 analog, 31-amino-acid peptide)

Status:

FDA-approved (Victoza 2010, Saxenda 2014 for obesity)

Mechanism:

A 31-amino-acid GLP-1 analog with a C16 fatty-acid chain (palmitoyl) attached to Lys26 via a gamma-glutamic acid spacer. This fatty-acid modification enables reversible binding to serum albumin, extending the half-life to ~13 hours. Activates GLP-1R to enhance glucose-dependent insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite.

EC50 (GLP1R Ec50):

~10 nM

Source:

DrugBank: DB06655; Knudsen LB, et al. J Med Chem. 2000;43(9):1664-1669.DOI

Clinical Development:

NCT00781922; NCT01272219

FDA:

Victoza, Saxenda (approved 2010-01-25)

References

ChEMBL:

CHEMBL1213363

DrugBank:

DB06655

KEGG DRUG:

D09199

PubChem:

PubChem

Literature:

FDA: Victoza (NDA 022341); NEJM: Marso et al. (2016) — LEADER CV outcomes

Disclaimer:

Liraglutide is FDA-approved as a prescription medicine (Victoza for T2DM, Saxenda for obesity). This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Liraglutide Properties 

Hazard Identification

Classification of the substance or mixture

Carcinogenicity, Category 2

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H351 Suspected of causing cancer H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Liraglutide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

18 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Liraglutide	1.00 KG	Oct 8, 2024
United Kingdom	Liraglutide	20 MG	Jul 8, 2026
United States	liraglutide	1 MT	Nov 22, 2025
United States	Liraglutide	1 KG	Aug 13, 2025
Sweden	liraglutide	1 KG	Aug 4, 2025
United States	MIC	2 MT	May 20, 2026
United States	liraglutide	1	Jan 21, 2026
Canada	Liraglutide	1 KG	Dec 8, 2025
Brazil	Liraglutida	1 G	Sep 29, 2025
Turkey	Liraglutide	5 MG	Jul 4, 2025
Reunion Island	Liraglutide	1 G	Apr 14, 2025
United States	Mic (Lipo C with B12), VIP, Ss31, glutathione and, Reta	50 MG	Mar 4, 2026
India	liraglutide	1 KG	Feb 25, 2026
United States	Liraglut	1 MT	Feb 9, 2025
India	Liraglutide	10 G	Jun 26, 2024
India	Liraglutide	100 G	Mar 4, 2024
United States	Semaglutide Liraglutide powder	10 G	Feb 20, 2024
India	Semaglutide	1.00 KG	Oct 8, 2024

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Liraglutide 95.0%~105.0% White or almost white loose powder HANDOM CHEM

Product Description

Seller Information