6-DIAZO-5-OXO-L-NORLEUCINE 99% solid
ISO FDA 29 Inquiries
157-03-9
Pharmaceutical Grade
99%
shanghai
25kg
2023-07-31
chemicals,low price LCZ696 Intermediate,NICOTINAMIDE RIBOSIDE,NR,,4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine,Romidepsin (FK228, Depsipeptide),Alpha-GPC
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceSlightly yellow powder
6-diazo-5-oxo-L-norleucine is a non-proteinogenic L-alpha-amino acid that is L-norleucine which is substituted at position 5 by an oxo group and at position 6 by a diazo group. It is as inhibitor of various glutamine-utilising enzymes. It has a role as a bacterial metabolite, an analgesic, an antibacterial agent, an antiviral agent, an antineoplastic agent, an EC 6.3.5.5 [carbamoyl-phosphate synthase (glutamine-hydrolysing)] inhibitor, an EC 6.3.4.2 [CTP synthase (glutamine hydrolyzing)] inhibitor, an EC 6.3.5.3 (phosphoribosylformylglycinamidine synthase) inhibitor, an EC 6.3.5.2 [GMP synthase (glutamine-hydrolysing)] inhibitor, an antimetabolite, a glutamine antagonist, an apoptosis inducer, an EC 2.4.2.14 (amidophosphoribosyltransferase) inhibitor, an EC 3.5.1.2 (glutaminase) inhibitor, an EC 6.3.5.1 [NAD(+) synthase (glutamine-hydrolysing)] inhibitor and an EC 6.3.5.4 [asparagine synthase (glutamine-hydrolysing)] inhibitor. It is a non-proteinogenic L-alpha-amino acid, a diazo compound and a ketone.|An amino acid that inhibits phosphate-activated glutaminase and interferes with glutamine metabolism. It is an antineoplastic antibiotic produced by an unidentified species of Streptomyces from Peruvian soil. (From Merck Index, 11th ed)CertificatesBasic Info-
Product Name:
6-Diazo-5-oxo-L-norleucine
Other Name:L-Norleucine,6-diazo-5-oxo-;Norleucine,6-diazo-5-oxo-,L-;6-Diazo-5-oxo-L-norleucine;DON;NSC 7365;DON (pharmaceutical);L-DON;L-6-Diazo-5-oxonorleucine;(2S)-2-Amino-6-diazo-5-oxohexanoic acid;543-31-7;15440-70-7;945678-45-5;2180165-45-9
CAS No.:157-03-9
Molecular Formula:C6H9N3O3
InChIKeys:InChIKey=YCWQAMGASJSUIP-YFKPBYRVSA-N
Molecular Weight:171.15
Exact Mass:171.06400
UNII:03J0H273KZ
HScode:2927000090
Categories:
Characteristics-
PSA:
117.78000
Appearance:light yellow crystalline
Density:1.3994 (rough estimate)
Melting Point:145-155 °C (decomp)
Boiling Point:301.12°C (rough estimate)
Refractive Index:1.5800 (estimate)
Storage Conditions:−20°C
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 3, Oral
Acute toxicity - Category 3, Dermal
Acute toxicity - Category 3, Inhalation
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H301 Toxic if swallowed
H311 Toxic in contact with skin
H331 Toxic if inhaled
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
chemicals,low price LCZ696 Intermediate,NICOTINAMIDE RIBOSIDE,NR,,4-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine,Romidepsin (FK228, Depsipeptide),Alpha-GPC
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Location:
No 7 ,Huacai International Building,Dengcai Road,Sandun,Westlake District,Hangzhou,Zhejiang
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Payment Terms:
L/C,100% TT in advance
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Average lead Time:
30 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
101-200
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Year of Establishment:
2011
Company Certificates-
ISO
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FDA
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CE
Gihi Chemicals: is specialized in the production of ester products which are used in the daily dietary supplements chemicals ,cosmetic products and skincare products since 1999.
Since 2010,GIHI CHEMICALS , begun to focus on the development and production of high-quality healthy Dietary supplements for our global high-reputation customers. The purity of all healthy Dietary supplements we provide has reached more than 99% purity. From the beginning of our products’ development, our technical engineers have chosen and design the production routes to ensure that we have been able to use biological, enzyme and water-phase green synthesis methods during the large production process to ensure that our health dietary supplements is truly high-quality ,green &environmental friendly, which are truly good and health to the human body.
Now our company has:
1 sales & management center + 3 research centers+ 4 production factories.
with ISO9001 & FDA certificate & CE certificate, accordance with GMP requirements.
1 Sales &Management center:
Add:No.567 Dengcai Street, Sandun, Westlake District, Hangzhou 310030, Zhejiang, China.
Research Center 1: (Chemical synthesis lab)
No.6, Chanyexietongchuanxing Center, Kangyang Road, Shangyu Economic and Technological Development Zone, Shaoxing, Zhejiang,China.
This research center: is specialized in chemical synthesis, our this research center could synthesis more than 300 new chemical products for many china pharmaceutical companies every year.
Research Center 2:(For Enzyme biology technical and Enzyme catalyst technical)
No.7, Lixiangxi Road, changsha Economic and Technological Development Zone, Changsha, Hunan.
Our this research center is committed to the applications of immobilized enzymes technology to the development of products such as peptides, polysaccharides, and non-natural amino acids. The products developed are widely used in medicine, health products, cosmetics, food, feed and other industries. The company adopts multidisciplinary technologies of chemistry, materials science and life sciences, which helps to meet the demand of green production while improving product quality and economic benefits. And also helps to reduces the emission of "three industrial pollution" greatly.
Research Center 3:(Biology enzyme-catalytic products)
No.2 Bio-hatch Building,No.10 Gaoxinzhongyidao, Yuehai Street,Nanshan District, Shenzhen, Guangdong, China.
This research center is specialized in biosynthesis technology as the core technology, and multi-disciplinary cross-application as target. We are the first batch company in the world to apply enzyme catalysis technology to the large-scale production of peptides, carbohydrates and nucleic acids and other special functional raw materials, and actively explore products in new application in the field. In this center, we used enzyme catalyst production methods to produce many high lever products, such as: NMN, (S)-Prox-ylane, Ectoin, Ergothioneine,etc.
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Inquiry History29 Inquiries
Country Product Purchase Quantity Date Posted
Romania
6-Diazo-5-oxo-L-norleucine
2000 MG Nov 12, 2024
Croatia
6-DIAZO-5-OXO-L-NORLEUCINE
25 G Sep 4, 2024
Nigeria
6-Diazo-5-oxo-l-norleucine
10 G Jul 21, 2024
Australia
6-Diazo-5-Oxo- Norleucine
1000 MT Jul 10, 2024
Austria
6-Diazo-5-oxo-L-nor-Leucine
1 G May 14, 2024
Italy
6-Diazo-5-Oxo-L-Norleucine (DON)
10 G Mar 4, 2024
Australia
6-diazo-5-oxo-L-norleucine
500 Jan 25, 2024
Czech
6-DIAZO-5-OXO-L-NORLEUCINE
25 KG Jan 4, 2024
United Kingdom
6-DIAZO-5-OXO-L-NORLEUCINE
5 G May 5, 2026
United Kingdom
6-Diazo-5-oxo-L-norleucine
1650 MG Oct 15, 2024
Colombia
6 Diazo 5 Oxo L Norleucine
300 MG Jul 18, 2024
Cayman Islands
6-DIAZO-5-OXO-L-NORLEUCINE 97%
3 G Jul 13, 2024
Czech
6-DIAZO-5-OXO-L-NORLEUCINE
50 G May 9, 2024
Australia
6-Diazo-5-Oxo-L-Norleucine
10 KG Jan 19, 2024
United States
6-DIAZO-5-OXO-L-NORLEUCINE
10 G Jan 5, 2024
United States
Pharmacy Grade C6H9N3O3
250 G Dec 17, 2023
France
6-DIAZO-5-OXO-L-NORLEUCINE 99% Powder Pharmacy Grade C6H9N3O3 Top Purity Senwayer
1 20' Fcl Oct 28, 2023
United States
6-Diazo-5-oxo-L-norleucine
1 KG Sep 1, 2025
Uzbekistan
6-DIAZO-5-OXO-L-NORLEUCINE
1 KG May 29, 2025
United States
6-DIAZO-5-OXO-L-NORLEUCINE
12 MT Nov 18, 2024 Post an enquiry for this product
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