CUCURBITACIN B 99% white powder kanbei
GMP ISO
6199-67-3
Industrial Grade
99%
qingdao
kanbei
25kg drum
2022-07-18
PVC resin,pvc paste resin,melamine
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Product Details
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Seller Information
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DescriptionECHEMI Editorial ReferenceCucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids; could repress cancer cell progression.IC50 value:Target: anticancer natural compoundin vitro: Cucurbitacin-B inhibited growth and modulated expression of cell-cycle regulators in SHSY5Y cells. At the molecular level, we found that Cucurbitacin-B inhibited AKT signaling activation through up-regulation of PTEN [1]. CuB induced apoptosis of A549 cells in a -concentration-dependent manner, as determined by fluorCertificatesBasic Info
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Product Name:
(+)-Cucurbitacin B
Other Name:19-Norlanosta-5,23-diene-3,11,22-trione,25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-,(2β,9β,10α,16α,23E)-;19-Nor-9β,10α-lanosta-5,23-diene-3,11,22-trione,2β,16α,20,25-tetrahydroxy-9-methyl-,25-acetate;(2β,9β,10α,16α,23E)-25-(Acetyloxy)-2,16,20-trihydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione;Cucurbitacin B;Cucurbitacine B;Amarine;NSC 144154;NSC 49451;(+)-Cucurbitacin B;HY-N 0416;120614-91-7;22076-50-2
CAS No.:6199-67-3
Molecular Formula:C32H46O8
InChIKeys:InChIKey=IXQKXEUSCPEQRD-DKRGWESNSA-N
Molecular Weight:558.7
Exact Mass:558.70
HScode:29153900
Categories:
Characteristics-
PSA:
138
XLogP3:2.6
Appearance:white to beige
Density:1.2±0.1 g/cm3
Melting Point:184-186 °C
Boiling Point:699.3±55.0°C at 760 mmHg
Flash Point:218.8±25.0 °C
Refractive Index:1.568
Water Solubility:DMSO: soluble 10mg/mL, clear
Storage Conditions:2-8°C
Toxicity:Oral-Mouse LD50: 14 mg/kg; Abdominal cavity-mouse LD50: 1 mg/kg
Flammability characteristics:Flammable, spicy and irritating smoke emitted from the fire
Specific rotation:D25 +88° (c = 1.55 in ethanol)
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 2, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
PVC resin,pvc paste resin,melamine
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Location:
Room 405, Unit 2, Building 1, Taiji Mansion, No. 38, Nanyang Road, Jinshui District, Zhengzhou City, Henan Province
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Payment Terms:
TT against copy of documents,L/C
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Average lead Time:
90 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
11-50
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Year of Establishment:
2022
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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