Cinobufotalin 99% Dideu
1108-68-5
Pharmaceutical Grade
99%
ShangHai
Dideu
25kg/Cardboard Drum
Yes
2023-07-24
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceCinobufotalin is one of the bufadienolides prepared from toad venom; has anticancer activity.IC50 value:Target:in vitro: Cinobufotalin(CB) caused significant DNA fragmentation, decrease of MMP, and an increase in the intracellular Ca(2+) ion and ROS production. In addition, CB induced upregulation of Fas protein, proteolytic activation of cytochrome c, caspase-2, -3, -8 and -9 together with the activation of Bid and Bax [1]. cinobufotalin displayed considerable cytotoxicity against lung
Cinobufotalin is a steroid lactone. It derives from a bufanolide.Basic Info-
Product Name:
Cinobufotalin
Other Name:Bufa-20,22-dienolide,16-(acetyloxy)-14,15-epoxy-3,5-dihydroxy-,(3β,5β,15β,16β)-;5β-Bufa-20,22-dienolide,14,15β-epoxy-3β,5,16β-trihydroxy-,16-acetate;Cinobufotalin;14,15-Epoxy-14H-cyclopenta[a]phenanthrene,bufa-20,22-dienolide deriv.;(3β,5β,15β,16β)-16-(Acetyloxy)-14,15-epoxy-3,5-dihydroxybufa-20,22-dienolide;NSC 90326
CAS No.:1108-68-5
Molecular Formula:C26H34O7
InChIKeys:InChIKey=KBKUJJFDSHBPPA-ZNCGZLKOSA-N
Molecular Weight:458.54
Exact Mass:458.54
Categories:
Characteristics-
PSA:
109.50000
XLogP3:0.79
Density:1.34±0.1 g/cm3(Predicted)
Melting Point:260.5 °C
Boiling Point:627.3±55.0 °C(Predicted)
Flash Point:210.7±25.0 °C
Refractive Index:1.612
Storage Conditions:2-8°C
Vapor Pressure:2.28E-18mmHg at 25°C
Specific rotation:D20 +11°
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 2, Oral
Acute toxicity - Category 2, Dermal
Acute toxicity - Category 1, Inhalation
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Danger
Hazard statement(s) H300 Fatal if swallowed
H310 Fatal in contact with skin
H330 Fatal if inhaled
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P262 Do not get in eyes, on skin, or on clothing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P284 [In case of inadequate ventilation] wear respiratory protection.
Response P301+P316 IF SWALLOWED: Get emergency medical help immediately.
P321 Specific treatment (see ... on this label).
P330 Rinse mouth.
P302+P352 IF ON SKIN: Wash with plenty of water/...
P316 Get emergency medical help immediately.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P320 Specific treatment is urgent (see ... on this label).
Storage P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst
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Location:
https://www.dideu.com/en/
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
7 days
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Total Annual Revenue:
Above $100 million
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Total Employees:
Above 1000
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Year of Establishment:
2016
Company Certificates-
ISO Certificate
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REACH
">Company Profile -
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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