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Chenodeoxycholic Acid CDCA

3 Inquiries

Unit Price: Get Latest Price
CAS No.:

474-25-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

ONERBIO

Packaging:

25kg/drum

Price valid (until):

2026-06-27

Company Type:
Distributor
Location:
China
Qualification:
Main Products:

Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Product Name: Chenodeoxycholic acid
    Synonyms: CDCA
    CAS: 474-25-9
    MF: C24H40O4
    MW: 392.57
    EINECS: 207-481-8
    Appearance: White powder





    Test Items

    Specifications

    Results

    Appearance

    Almost white powder

    conform

    Solubility

    Soluble in water and in isotonic solutions, practically insoluble in organic solvents

    Conform

    Identification A

    Positive

    Conform

    Identification B

    Positive

    Conform

    Appearance of solution

    Solution is clear

    conform

    Absorbance

    A 0.80

    0.62

    Aprotinin oligomers

    1.0%

    0.72%

    Loss on drying

    6.0 % (0.100 g , drying in vacuo)

    5.2%

    Purity

    98%

    99.62%

    PH

    5.0 -7.0  

    6.0

    Bacterial endotoxins

    0.14 EU/ Ph.Eur.U.

    Conform

    Abnormal toxicity

    Non toxic (2 Ph.Eur.U. / ml , 0.5 ml)

    Conform

    Pyrogens

    Absent at 15Ph.Eur.U./ kg / rabbit

    Conform

    Microbial Limit

    TAMC : 100  CFU/1g

    TYMC : 10  CFU/1g

    Conform

    Enterobacterias resistant to bile , Pseudomonas aeruginosa and Staphylococcus aureus should be absent in 1g .

    Conform

    Conclusion

    Comply to Enterprise standard


    1. Chenodeoxycholic acid is widely utilized in therapeutic applications. It is applied in medical therapy to dissolve gallstones. It is employed in the treatment of cerebrotendineous xanthomatosis. It is used to treat constipation and cerebrotendineous xanthomatosis. It acts as a urea receptor in supramolecular chemistry which can contain anions. It is a staining additive commonly used with ruthenium or organic photo-sensitizers in the preparation of staining solutions for dye solar cells.

    2. Chenodeoxycholic Acid is a staining additive commonly used with ruthenium or organic photo-sensitizers in the preparation of staining solutions for Dye Solar Cells. This co-adsorbent will prevent dye aggregation on the semiconductor surface, reducing losses in the solar cell's operation.

    3. Chenodeoxycholic Acid is a white solid added with the dye powder to the solvent while preparing staining solutions. The concentration of co-adsorbent is typically 10 fold the dye concentration.

    4. Chenodeoxycholic acid has been used in a study to assess its effects as a long-term replacement therapy for cerebrotendinous xanthomatosis (CTX).

    5. It has also been used in a study to investigate its effects on the small-intestinal absorption of bile acids in patients with ileostomies.

    6. Chenodeoxycholic acid (CDCA) is a hydrophobic primary bile acid that activates nuclear receptors involved in cholesterol metabolism.EC50 concentrations for activation of FXR range from 13-34 μM.In cells, CDCA also binds to bile acid binding proteins (BABP) with a reported stoichiometry of 1:2.CDCA toxicity is linked to increased cellular glutathione levels and increased oxidative stress. Exposure of cells to excess CDCA contributes to liver and intestinal cancers.

    Basic Info
    Product Name:

    Chenodeoxycholic acid

    Other Name:

    Cholan-24-oic acid,3,7-dihydroxy-,(3α,5β,7α)-;5β-Cholan-24-oic acid,3α,7α-dihydroxy-;5β-Cholanic acid,3α,7α-dihydroxy-;(3α,5β,7α)-3,7-Dihydroxycholan-24-oic acid;Anthropodeoxycholic acid;Anthropodesoxycholic acid;Chenodeoxycholic acid;Chenodesoxycholic acid;3α,7α-Dihydroxycholanic acid;Gallodesoxycholic acid;17β-(1-Methyl-3-carboxypropyl)etiocholane-3α,7α-diol;3α,7α-Dihydroxy-5β-cholanic acid;3α,7α-Dihydroxy-5β-cholanoic acid;Anthropododesoxycholic acid;CDC;3α,7α-Dihydroxy-5β-cholan-24-oic acid;Chenic acid;Chendol;Chenodiol;7α-Hydroxylithocholic acid;Chenofalk;Chenix;Chenocol;Chenodex;Hekbilin;Ulmenide;Cholanorm;Fluibil;Chenocedon;Kebilis;Chenossil;(+)-Chenodeoxycholic acid

    CAS No.:

    474-25-9

    Molecular Formula:

    C24H40O4

    InChIKeys:

    InChIKey=RUDATBOHQWOJDD-BSWAIDMHSA-N

    Molecular Weight:

    392.57200

    Exact Mass:

    392.57

    EC Number:

    207-481-8

    UNII:

    0GEI24LG0J

    DSSTox ID:

    DTXSID2020260

    ATC Code:

    A05AA01|A - Alimentary tract and metabolism

    HScode:

    2918990090

    Characteristics
    PSA:

    77.76000

    XLogP3:

    4.47790

    Appearance:

    white to off-white crystalline powder

    Density:

    1.128g/cm3

    Melting Point:

    119 °C

    Boiling Point:

    547.1ºC at 760 mmHg

    Flash Point:

    298.8ºC

    Refractive Index:

    1.558

    Water Solubility:

    Practically insoluble in water

    Storage Conditions:

    Store in a cool, dry place. Store in a tightly closed container.

    Collision Cross Section:

    201.51 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|206.57 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|202.3 Ų [M-H]- [CCS Type: DT, Method: single field calibrated]|186.9 Ų [M+H-2H2O]+ [CCS Type: DT, Method: single field calibrated]|202.8 Ų [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated]|201.9 Ų [M+HCOO]- [CCS Type: DT, Method: single field calibrated]|208.5 Ų [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|224.5 Ų [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|199.2 Ų [M+Na-H+Cl]- [CCS Type: DT, Method: single field calibrated]|205.8 Ų [M+Na-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|205.9 Ų [M-H]-

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Nutrition supplement material,Pharmaceutical raw material,Chemical raw material

    Location:

    Changqing 5th Road, Jianghan District

    Payment Terms:

    TT against copy of documents

    Average lead Time:

    5

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2020

    Wuhan Oner Biotech Co.,Ltd. located in the popular city of Wuhan, specilize in producing and developing pharmaceutical & its intermediates, Cosmetics Raw Material and Intermediate, food additive, Plant extracts,and in distributing the products of our own company. We serves our clients by supplying high-quality.These products are manufactured in ISO 9001 certified plants and have continuously been passing quality inspection by CIQ (China Entry & Exit Inspection and Quarantine Bureau),100% pass rate. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , the products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Pharmaceutical Chenodeoxycholic Acid CAS 474-25-9 Purity 99% with USP Standard

    1000 KG Jul 11, 2023
    India

    Pharmaceutical Chenodeoxycholic Acid CAS 474-25-9 Purity 99% with USP Standard

    1000 KG Aug 30, 2023
    India

    Chenodeoxycholic Acid

    5 KG Mar 18, 2026
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