China Largest factory Manufacturer Supply High Qulity 6,7-Dihydroxycoumarin/Esculetin CAS 305-01-1
GMP HALAL KOSHER ISO FDA TDS
305-01-1
Food Grade
99%
Shanghai
Leader
190KG/Drum
Yes
2023-12-18
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceEsculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities[1].
Solid
Esculetin is a hydroxycoumarin that is umbelliferone in which the hydrogen at position 6 is substituted by a hydroxy group. It is used in filters for absorption of ultraviolet light. It has a role as an antioxidant, an ultraviolet filter and a plant metabolite.Certificates-
TDS
Basic Info-
Product Name:
Esculetin
Other Name:2H-1-Benzopyran-2-one,6,7-dihydroxy-;Coumarin,6,7-dihydroxy-;Esculetin;6,7-Dihydroxy-2H-1-benzopyran-2-one;Cichorigenin;Cichoriin aglycon;6,7-Dihydroxycoumarin;Esculetol;Esculin aglycon;Aesculetin;Asculetine;NSC 26428;6,7-Dihydroxy-2-benzopyrone
CAS No.:305-01-1
Molecular Formula:C9H6O4
InChIKeys:InChIKey=ILEDWLMCKZNDJK-UHFFFAOYSA-N
Molecular Weight:178.14
Exact Mass:178.14
BRN:152788
EC Number:206-161-5
UNII:SM2XD6V944
NSC Number:26428
DSSTox ID:DTXSID3075383
HScode:2932209090
Categories:
Characteristics-
PSA:
66.8
XLogP3:1.2
Appearance:Light yellow powder
Density:1.56 g/cm3
Melting Point:276 °C
Boiling Point:469.7°C at 760 mmHg
Flash Point:201.5±22.2 °C
Refractive Index:1.689
Water Solubility:Solubility Almost insoluble in boiling water, ether; soluble in hot ethanol, glacial acetic acid
Storage Conditions:2-8°C
Collision Cross Section:129.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
Above 1000
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Year of Establishment:
2014
Company Certificates-
Level A of Tax Credit Registration Assessment by Government
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Good Product Quality Management Certificate of Shanxi Province,China
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Company Trade Union Qualification Certificate
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Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
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AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
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FDA
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Country Product Purchase Quantity Date Posted Post an enquiry for this product
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