China Most Professional Factory Supply High Qulity Gadoteridol CAS 120066-54-8
GMP HALAL KOSHER ISO FDA TDS 1 Inquiries
120066-54-8
Pharmaceutical Grade
99%
Shanghai
Leader
25KG/Drum
Yes
2024-01-09
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceGadoteridol provides contrast enhancement of the brain, spine and surrounding tissues resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or those thought to cause a disruption of the normal blood brain barrier. Gadoteridol can also be used for whole body contrast enhanced MRI including the head, neck, liver, breast, musculoskeletal system and soft tissue pathologies. n MRI, visualization of normal and pathological brain tissue depends in part on variations in the radiofrequency signal intensity that occur with changes in proton density, alteration of the T1, and variation in T2. When placed in a magnetic field, gadoteridol shortens the T1 relaxation time in tissues where it accumulates. Abnormal vascularity or disruption of the blood-brain barrier allows accumulation of gadoteridol in lesions such as neoplasms, abscesses, and subacute infarcts.
Indocyanine Green (ICG, IC Green, Foxgreen) is a negatively charged tricarbocyanine dye widely used for imaging and flow cytometry due to its low toxicity and near-infrared fluorescence emission.ICG has an absorption maximum at 787 nm with slight absorption in the visible range and a fluorescence emission maximum at 819 nm. The minimal light scattering and low autofluorescence in this spectral range result in a significantly reduced background and improved signal-to-noise ratios, thereby enhancing detection sensitivity.ICG maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach ICG fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cystines should be reduced with TCEP (tris-carboxyethylphosphine) or with another appropriate reductant prior to the labeling.
ChEBI: A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).
Gadoteridol is a nonionicclear, colorless to slightly yellow, gadolinium-based contrastagent indicated to visualize lesions with abnormal vascularityin the CNS, head, and neck. It is a hypertonic solutionwith an osmolality of 2.2 times that of plasma. Clinical enhancementof images occurs primarily when using T1-weighted sequences.Certificates-
TDS
Basic Info-
Product Name:
Gadoteridol
Other Name:gadotridol;triSulfo-Cy5.5 hydrazide;triSulfo-Cy5.5 Maleimide;ICG-Hydrazide;diSulfo-ICG Hydrazide;ICG-Maleimide;diSulfo-ICG Maleimide;disulfo-ICG-NHS
CAS No.:120066-54-8
Molecular Formula:C17H28GdN4O7
InChIKeys:JOJFJDKAWWEUPD-UHFFFAOYSA-K
Molecular Weight:557.68
Exact Mass:559.12774
EC Number:1533716-785-6
DSSTox ID:DTXSID2048662
Color/Form:White to off-white
ATC Code:V08CA04|V - Various
HScode:2942000000
Categories:
Characteristics-
XLogP3:
log Kow = -3.68 (octanol/water); logP = -1.98 (butanol/water), at pH 7
Density:Osmolality (37 °C): 630 mOsM/kg water; viscosity (cP): 2.0 (20 °C), 1.3 (37 °C); density at 25 °C 1.140. /Gadoteridol injection/
Melting Point:188-193 °C
Water Solubility:In water, 737 mg/mL|Solubility (mg/mL): methanol 119, isopropanol 41, dimethylformamide 10.1, acetonitrile 6.1, methylene chloride 5.2, ethyl acetate 0.5, acetone 0.4, hexane 0.2, toluene 0.3
Storage Conditions:ProHance (Gadoteridol) Injection should be stored at 25 °C (77 °F) excursions permitted to 15-30 °C (59- 86 °F). Protect from light. Do not freeze.
Experimental Properties:Hydrophilic
Critical Temperature & Pressure:Store at -20°C
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Seller Information
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Business Type:
Manufactory
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Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
Above 1000
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Year of Establishment:
2014
Company Certificates-
Level A of Tax Credit Registration Assessment by Government
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Good Product Quality Management Certificate of Shanxi Province,China
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Company Trade Union Qualification Certificate
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Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina
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AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China
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FDA
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Inquiry History1 Inquiries
Country Product Purchase Quantity Date Posted
India
Gadoteridol
800 MG Jul 8, 2025 Post an enquiry for this product
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