China Largest Manufacturer Supply High Purity Pyrante CAS 15686-83-6
GMP HALAL KOSHER ISO FDA TDS
15686-83-6
Pharmaceutical Grade
99%
Shanghai
Leader
25KG/Drum
2024-01-14
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceChEBI: A carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoa e)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'.
Pyrantel is a carboxamidine that is 1,4,5,6-tetrahydropyrimidine that is substituted at position 1 by a methyl group and at position 2 by an (E)-2-(2-thienyl)vinyl group. It is used, particularly as the embonate [4,4'-methylenebis(3-hydroxy-2-naphthoate)] salt, as an anthelmintic that is effective against intestinal nematodes including threadworms, roundworms and hookworms, and is included in the WHO 'Model List of Essential Medicines'. It has a role as an antinematodal drug. It is a member of thiophenes, a carboxamidine and a member of 1,4,5,6-tetrahydropyrimidines.|Pyrantel is a pyrimidine-derivative anthelmintic agent for the oral treatment of various parasitic worm infections including ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. Pyrantel was initially described in 1965 by researchers from Pfizer who sought cyclic amidines with suitable pharmacokinetic properties (specifically, duration of action) for use as an anthelmintic drug. Pyrantel is mainly available in formulations for dogs and cats as the embonate salt, containing a 34.7% pyrantel base. Pyrantel is on the World Health Organization's List of Essential Medicines, which are the safest and most effective medicines required in a functioning health system,. A depolarizing neuromuscular-blocking agent causing longstanding nicotinic receptor activation, resulting in spastic paralysis of susceptible nematodes (worms). Pyrantel has shown to be effective after a single dose. In humans, it is administered as pyrantel pamoate,,,.|Pyrantel is a nonabsorbed anthelmintic agent with activity against intestinal nematodes such as pinworms and roundworms. Pyrantel therapy has not been reported to cause serum aminotransferase elevations or clinically apparent liver injury.|A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It is a drug of second-choice after benzimidazoles for treatment of ascariasis, hookworm, and pinworm infections, being effective after a single dose. (From Smith and Reynard, Textbook of Pharmacology, 1992, p920)Certificates-
TDS
Basic Info-
Product Name:
Pyrantel
Other Name:Pyrimidine,1,4,5,6-tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]-;Pyrimidine,1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]-,(E)-;Pyrimidine,1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)ethenyl]-,(E)-;1,4,5,6-Tetrahydro-1-methyl-2-[(1E)-2-(2-thienyl)ethenyl]pyrimidine;Pyrantel;1,4,5,6-Tetrahydro-1-methyl-2-[trans-2-(2-thienyl)vinyl]pyrimidine;Pyrequan;Ascarel
CAS No.:15686-83-6
Molecular Formula:C11H14N2S
InChIKeys:InChIKey=YSAUAVHXTIETRK-AATRIKPKSA-N
Molecular Weight:594.685
Exact Mass:206.31
EC Number:239-774-1
UNII:4QIH0N49E7
DSSTox ID:DTXSID5023538
Color/Form:Crystals from methanol|Yellow, crystalline solid
ATC Code:P - Antiparasitic products, insecticides and repellents
HScode:2934999090
Categories:
Characteristics-
PSA:
43.8
XLogP3:6.26020
Density:1.13±0.1 g/cm3(Predicted)
Melting Point:178-179 °C
Boiling Point:324.4±44.0 °C(Predicted)
Flash Point:150ºC
Water Solubility:Insoluble in water, slightly soluble in dimethylformamide, and soluble in dimethyl sulfoxide.
Odor:Odorless
Taste:Tasteless
Collision Cross Section:143 Ų [M+H]+ [CCS Type: TW]
Hazard IdentificationClassification of the substance or mixture
no data available
GHS label elements, including precautionary statements
Pictogram(s) no data available Signal word no data available
Hazard statement(s) no data available
Precautionary statement(s) Prevention no data available
Response no data available
Storage no data available
Disposal no data available
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients
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Location:
National Aerospace Economic & Technical Development Zone,Chang'an,Xi'an,China
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
5
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
Above 1000
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Year of Establishment:
2014
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Certifications:
Level A of Tax Credit Registration Assessment by Government,Good Product Quality Management Certificate of Shanxi Province,China,Company Trade Union Qualification Certificate,Excellent Group Enterprise of Quality and credit in Shaanxi ProvinceChina,AAA TOP Credit Excellent Group Enterprise of Shanxi Province,China,FDA
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