Amino acid,intermediates
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Product Description
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Seller Information
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DescriptionECHEMI Editorial ReferenceWhite SolidChEBI: The dihydrate of the anhydrous form of cidofovir. A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.
Cidofovir dihydrate is the dihydrate of the anhydrous form of cidofovir. A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients. It has a role as an antiviral drug and an antineoplastic agent. It contains a member of cidofovir anhydrous.|Cidofovir is a synthetic, acyclic, monophosphate nucleotide analog of deoxycytidine with antiviral activity, and mostly used against cytomegalovirus (CMV). After incorporation into the host cell, cidofovir is phosphorylated by pyruvate kinases to its active metabolite cidofovir diphosphate. Cidofovir diphosphate, bearing structural similarity to nucleotides, competes with deoxycytosine-5-triphosphate (dCTP) for viral DNA polymerase and gets incorporated into the growing viral DNA strands. As a result, it prevents further DNA polymerization and disrupts DNA replication of viruses.|An acyclic nucleoside phosphonate that acts as a competitive inhibitor of viral DNA polymerases. It is used in the treatment of RETINITIS caused by CYTOMEGALOVIRUS INFECTIONS and may also be useful for treating HERPESVIRUS INFECTIONS.Basic Info-
Product Name:
Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, hydrate (1:2)
Other Name:Phosphonic acid,P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-,hydrate (1:2);Phosphonic acid,[[2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-,dihydrate,(S)-;Phosphonic acid,[[(S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-,dihydrate;Cidofovir hydrate
CAS No.:149394-66-1
Molecular Formula:C8H14N3O6P.2H2O
InChIKeys:InChIKey=FPKARFMSZDBYQF-ILKKLZGPSA-N
Molecular Weight:279.187021
Exact Mass:315.083
EC Number:1308068-626-2
UNII:JIL713Q00N
DSSTox ID:DTXSID6041002
NCI Thesaurus Code:C1600
HScode:2933599550
Categories:
Characteristics-
PSA:
148
Density:1.8±0.1 g/cm3
Melting Point:260 deg C (dec)
Flash Point:322.4±34.3 °C
Refractive Index:1.656
Water Solubility:Aqueous solubility >=170 mg/ml @ pH 6-8
Hazard IdentificationClassification of the substance or mixture
Germ cell mutagenicity, Category 2
Carcinogenicity, Category 2
Reproductive toxicity, Category 2
Specific target organ toxicity â single exposure, Category 2
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H341 Suspected of causing genetic defects
H351 Suspected of causing cancer
H361 Suspected of damaging fertility or the unborn child
H371 May cause damage to organs
Precautionary statement(s) Prevention P203 Obtain, read and follow all safety instructions before use.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P318 IF exposed or concerned, get medical advice.
P308+P316 IF exposed or concerned: Get emergency medical help immediately.
Storage P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
Amino acid,intermediates
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Location:
Room 403, 3-1, 4-1 (Industrial Design Center), No. 18, Wujiang Road, Wulidian Street, Jiangbei District, Chongqing City, China.
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Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
2
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Country Product Purchase Quantity Date Posted Post an enquiry for this product