High quality Tobramycin CAS NO.32986-56-4
5 Inquiries
32986-56-4
Pharmaceutical Grade
99%
shanghai
Lonwin
1kg/bag,25kg/drum,25kg/bag
Yes
2024-02-04
CHEMICALS,REAGENTS
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceTobramycin is an aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius.Target: AntibacterialTobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial infections, particularly Gram-negative infections. It is especially effective against species of Pseudomonas [1]. Tobramycin works by binding to a site on the bacterial 30S and 50S ribosome, preventing formation of the 70S complex. As a result, mRNA
Solid
Tobramycin is a amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring. It has a role as an antibacterial agent, an antimicrobial agent and a toxin. It derives from a kanamycin B. It is a conjugate base of a tobramycin(5+).|An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the pseudomonas species. It is a 10% component of the antibiotic complex, nebramycin, produced by the same species.|Tobramycin is an Aminoglycoside Antibacterial.|Tobramycin is a parenterally administered, broad spectrum aminoglycoside antibiotic that is widely used in the treatment of moderate to severe bacterial infections due to sensitive organisms. Despite its wide use, tobramycin has rarely been linked to instances of clinically apparent liver injury.|Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius with bacteriostatic activity. Following active transport into the cell, tobramycin binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, thereby inhibiting initiation of protein synthesis, consequently leading to bacterial cell death. In addition, tobramycin induces misreading of the mRNA template causing incorrect amino acids to be incorporated into the growing polypeptide chain, consequently interfering with protein elongation.|An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the PSEUDOMONAS species. It is a 10% component of the antibiotic complex, NEBRAMYCIN, produced by the same species.Basic Info-
Product Name:
Tobramycin
Other Name:D-Streptamine,O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-;O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribo-hexopyranosyl-(1→4)]-2-deoxy-D-streptamine;Nebramycin factor 6;Tobramycin;3′-Deoxykanamycin B;Nebramycin 6;Nebramycin VI;Deoxykanamycin B;Tobramycetin;Tobramicin;Tobralex;Tobrex;Tobramaxin;NF 6;Tobradistin;Tobracin;NSC 180514;Tobramax;Tobrin;Vantobra;Tobi Podhaler;11098-01-4;11111-45-8;34337-51-4;37321-13-4;54330-95-9;70322-33-7
CAS No.:32986-56-4
Molecular Formula:C18H37N5O9
InChIKeys:InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N
Molecular Weight:467.51
Exact Mass:467.51
EC Number:251-322-5
UNII:VZ8RRZ51VK
NSC Number:757352
DSSTox ID:DTXSID8023680
NCI Thesaurus Code:C62082
Color/Form:White to off-white powder|Crystals
ATC Code:J01GB01|J - Antiinfectives for systemic use|S - Sensory organs
HScode:29419090
Categories:
Characteristics-
PSA:
268
XLogP3:-6.2
Appearance:white to off-white
Density:1.5±0.1 g/cm3
Melting Point:164 °C
Boiling Point:741.6°C at 760 mmHg
Flash Point:422.8±32.9 °C
Refractive Index:1.651
Water Solubility:H2O: 50 mg/mL, clear, faintly yellow
Storage Conditions:2-8°C
Vapor Pressure:2.37X10-21 mm Hg at 25 deg C (est)
Toxicity:LD50 in mice, rats (mg/kg): 441, 969 s.c. (Welles)
Specific rotation:D20 +129° (c = 1 in water)
PH:Basic substance
Henrys Law Constant:Henry's Law constant = 2.24X10-39 atm-cu m/mol at 25 °C (est)
Dissociation Constants:pKb1 = 8.6; pKb2 = 8.8; pKb3 = 9.0 (amines) (est)
Experimental Properties:Hygroscopic
Hazard IdentificationClassification of the substance or mixture
Skin irritation, Category 2
Eye irritation, Category 2
Specific target organ toxicity â single exposure, Category 3
GHS label elements, including precautionary statements
Pictogram(s)
Signal word Warning
Hazard statement(s) H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
Response P302+P352 IF ON SKIN: Wash with plenty of water/...
P321 Specific treatment (see ... on this label).
P332+P317 If skin irritation occurs: Get medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P319 Get medical help if you feel unwell.
Storage P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Trader
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Main Products:
CHEMICALS,REAGENTS
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Location:
No 966 Huaxu Road, Qingpu District, Shanghai, 201702, P.R. China
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
10 days
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Total Annual Revenue:
$10 million-$25 million
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Total Employees:
11-50
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Year of Establishment:
2011
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Inquiry History5 Inquiries
Country Product Purchase Quantity Date Posted
Bulgaria
Tobramycin powder CAS 32986-56-4
50 G Oct 22, 2024
India
Tobramycin
5 MT Nov 14, 2025
Bangladesh
Tobramycin
1 KG Apr 13, 2026
Pakistan
Tobramycin
1 KG Mar 6, 2025
Pakistan
Tobramycin
2 Feb 23, 2024 Post an enquiry for this product
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