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China origin pharmaceutical peptide Sermaglutide

Name: China origin pharmaceutical peptide Sermaglutide
Brand: HANDOM CHEM
SKU: pr2401081594
Price: 265 USD
Availability: InStock

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CAS No.:

910463-68-2

Grade:

Pharmaceutical Grade

Port:

Shanghai or Beijing

Brand:

HANDOM CHEM

Packaging:

1g/Bottle, 3g/Bottle, 5g/Bottle, 10g/Bottle or according to the specific requirements from customers

Sample Available:

Yes

Price valid (until):

2024-02-08

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DALIAN HANDOM CHEMICALS CO.,LTD.

Company Type:

Manufactory

Location:

China

Payment Terms:

TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

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Product Description
Seller Information
Inquiry History

Description

Product Details

Product Name: Sermaglutide

Alias: Semaglutide

CAS No.: 910463-68-2

EINECS No.: 203-405-2

Molecular Formula: C187H291N45O59

Shop China origin pharmaceutical peptide Sermaglutide-Detailed Image 1

Sequence:

His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-N6-[N-(17-carboxy-1-oxoheptadecyl-L-γ-glutamyl[2-(2-aminoethoxy)ethoxy]acetyl[2-2-aminoethoxy)ethoxy]acetyl]-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH

Brief Introduction:

Semaglutide, also called sermaglutide, which is a GLP-1 receptor agonist developed by Novo Nordisk. This drug can increase glucose metabolism by stimulating pancreatic beta cells to secrete insulin; and inhibit pancreatic alpha cells from secreting glucagon to reduce fasting and postprandial blood sugar.
In addition, it can also reduce food intake by reducing appetite and slowing digestion in the stomach, ultimately reducing body fat and facilitating weight loss.

Shop China origin pharmaceutical peptide Sermaglutide-Detailed Image 2

Test Items		Specifications
Appearance		White or off-white powder
Solubility		Freely soluble in water; Firstly, to add freshly boiled and cooled water to make a clear solution containing 0.15mg of semaglutide in 1ml. Then, to adjust the pH of the solution to 5.5 with 0.05M hydrochloric acid and keep for 30 seconds. Finally, to adjust the pH of the solution to 3.0 and keep 30 seconds. The solution should be turbid in the range of pH 3.0 to 5.5.
Identification	HPLC	As obtained in the Assay, the difference between the retention time of the major peak of the sample solution and the reference solution should be less than 1 minute.
	Peptide Mapping	Peptide mapping of sample solution is similar to that of reference solution.
	N-terminal amino acid sequence	His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu
pH Value		7.0 ~ 8.0
Water Content (K. F)		Not more than 8.0%
Related Substances	Hydrophilic Impurities	Not more than 1.5%
	Hydrophobic Impurities 1	Not more than 1.0%
	Hydrophobic Impurities 2	Not more than 0.2%
	Total Impurities	Not more than 2.0%
High Molecular Weight Proteins		Not more than 0.2%
Residual Solvents	Ethanol	Not more than 0.5%
	Acetonitrile	Not more than 0.041%
	Dichloromethane	Not more than 0.06%
Biological Activity		Should be 0.7U ~ 1.3U per 1mg
Residual Host Cell Protein		Not more than 100ng/mg
Residual Host Cell DNA		Not more than 10ng/mg
Bacterial Endotoxins		Not more than 10EU/mg
Microbial Limits	Total Aerobic Microbial Count	Not more than 100CFU/g
Microbial Limits	Total Yeasts and Moulds Count	Not more than 100CFU/g
Assay(C187H291N45O59)		Containing Semaglutide 0.76mg ~ 1.00mg per 1mg

Applications:

Semaglutide is an antidiabetic drug used for the treatment of type 2 diabetes and long-term weight management.
New research finds that semaglutide also provides heart benefits in overweight non-diabetic patients, as well as treating alcohol addiction.

Packaging:

1g/Bottle, 3g/Bottle, 5g/Bottle, 10g/Bottle or according to the specific requirements from customers.

Shop China origin pharmaceutical peptide Sermaglutide-Detailed Image 3

Storage Conditions:

For short-term transportation, please keep it at 2-8℃. But please store it in unopened original containers at a temperature of -20±5℃ if for long-term storage (≥6 months); protected from direct sunlight, heat and moisture.

Shelf Life:

36 months if stored under above mentioned conditions.

ECHEMI Editorial Reference

Semaglutide (CAS: 910463‑68‑2) is a synthetic lipid‑modified peptide analogue, consisting of a 31‑amino‑acid backbone with a covalently attached C18 fatty di‑acid side‑chain via a hydrophilic spacer. It shares 94% amino‑acid sequence homology with native human GLP‑1 peptide. The substance appears as white to almost white hygroscopic powder, with molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and molecular weight of 4113.58 g/mol. Structural modifications grant it resistance against DPP‑4 enzymatic degradation and enable reversible binding to serum albumin, contributing to its extended in‑vivo half‑life property.

Certificates

Basic Info

Product Name:

Semaglutide

Other Name:

Sermaglutide;Semaglutide impurity;Sermaglutide USP/EP/BP;semaglutide;Sermaglutide CAS 910463 68 2;Semaglutide (H-7894.0001);semgalutide;Semaglutide

CAS No.:

910463-68-2

Molecular Formula:

C187H291N45O59

InChIKeys:

DLSWIYLPEUIQAV-CCUURXOWSA-N

Molecular Weight:

4113.57754

Exact Mass:

4113.122087 g/mol

EC Number:

203-405-2

Color/Form:

White to off-white

Categories:

Other Chemical Drugs

Characteristics

PSA:

1650 Å²

XLogP3:

5.44520

Critical Temperature & Pressure:

Store at -20°C

Research

Class:

GLP-1R agonist

Status:

FDA-approved (Ozempic / Wegovy / Rybelsus)

Mechanism:

Long-acting, selective glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. Engineered for extended half-life (~1 week) via albumin binding (fatty acid acylation at Lys26) and resistance to DPP-4 degradation (Aib substitution at position 8). Promotes insulin secretion, inhibits glucagon release, delays gastric emptying, and reduces appetite via central nervous system GLP-1R activation.

Activity note:

Potent, selective GLP-1R agonist. Reported binding affinity Ki = 0.38 ± 0.06 nM. Semaglutide is a human GLP-1 analog with structural modifications for albumin binding (C18 fatty diacid at Lys26) and enzymatic stability (Aib8 substitution).

Source:

Lau J, et al. J Med Chem. 2015;58(18):7370-7380. Wilding JPH, et al. N Engl J Med. 2021;384(11):989-1002.DOI

Clinical Development:

NCT03548935; NCT03552757; NCT01720446; NCT02692716

FDA:

Ozempic, Wegovy, Rybelsus (approved 2017-12-05)

References

ChEMBL:

DrugBank:

KEGG DRUG:

PubChem:

Literature:

NEJM: Wilding et al. (2021) — STEP-1; NEJM: Marso et al. (2016) — SUSTAIN-6; J Med Chem: Lau et al. (2015) — Discovery of Semaglutide; FDA: Ozempic (NDA 209637)

Disclaimer:

Semaglutide is approved as a prescription medicine (Ozempic, Wegovy, Rybelsus) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.

See More Semaglutide Properties 

Hazard Identification

Classification of the substance or mixture

Reproductive toxicity, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H361 Suspected of damaging fertility or the unborn child
Prevention	P203 Obtain, read and follow all safety instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
Response	P318 IF exposed or concerned, get medical advice.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Semaglutide Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine

Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
51-100

Year of Establishment:
2020

Dalian Handom Chemicals Co., Ltd.(HDC CHEM) is a professional 15-Year-Experienced Supplier of APIs & Intermediates, Pharmaceutical Excipients, Food & Nutraceutical Ingredients, Personal Care Chemicals and Specialty Chemicals from northeast of China, which strives to provide customers with high-quality products and comprehensive service across all over the world, our main products cover Retatrutide Lyophilized Powder, Retatrutide, Tirzepatide, Tirzepatide Lyophilized Powder, Semaglutide, Mazdutide, Cagrilintide, LL-37, Thymosin Alpha 1(Thymosin α1), MT-2, MOTS-c, HEP-1, TB-500, NAD+, GHK-Cu, Glow, Klow, Selank, Semax, Glutathione, 5-Amino-1MQ, ARA-290, SS-31, DSIP, SNAP-8, Medetomidine, Medetomidine Hydrochloride, Salcaprozate Sodium, Sodium 8-(2-hydroxybenzamido)octanoate, 2,6-Dimethyl Beta Cyclodextrin, mPEG-DMG-2K, mPEG-DSPE-2K, 1,2-Distearoyl-sn-3-phosphacholine(DSPC), 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine(DOPE), Pharmaceutical Grade Fructose, Lactose Anhydrous, Lactose Monohydrate, Orotic acid anhydrous, Orotic acid monohydrate, 6-Methyluracil, Chitosan, Mushroom Chitosan, Chitosan Hydrochloride, Chitosan Oligosaccharide, Alginate Oligosaccharide, Inulin, L-Serine, Mung Bean Peptide, Walnut Peptide, Rice Peptide, Oyster Peptide, Sea Cucumber Peptide, Hydrolyzed Keratin, Folic Acid, Vitamin E Acetate, Vitamin B2, Riboflavin Sodium Phosphate, Pyridoxal 5'-phosphate Monohydrate, Vegan Vitamin D3, Vitamin A Palmitate, Vitamin A Acetate, Apple Pectin, Citrus Pectin, Sunflower Pectin, Salidroside, Urolithin A, Milk Thistle Extract, Saffron Extract, Red Clover Extract, Sulforaphane, Glucoraphanin, Soy Isoflavones, Soy Lecithin, Soya Lecithin, Egg Yolk Lecithin, Phosphatidylserine, Cooling Agent WS-3, Cooling Agent WS-5, Cooling Agent WS-10, Cooling Agent WS-12, Cooling Agent WS-23, Cooling Agent WS-27, Menthyl Lactate, Menthyl PCA, Avobenzone, Benzophenone-3 (UV-9), Benzophenone-4 (UV-284), Bis-ethylhexyloxyphenol Methoxyphenyl Triazine (Bemotrizinol), Diethylaminohydroxybenzoyl Hexyl Benzoate (UVA Plus), Diethylhexyl Butamido Triazone (Iscotrizinol), Disodium Phenyl Dibenzimidazole Tetrasulfonate (DPDT), Ethylhexyl Triazone (UVT-150), Homosalate, Octocrylene, 2-Ethylhexyl Salicylate (Octyl Salicylate), 2-Ethylhexyl Trans-4-Methoxycinnamate (OMC), 2-Phenylbenzimidazole-5-Sulfonic Acid (UV-T), Lanolin Anhydrous, Palmitoyl Tripeptide-5, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Biotinoyl Tripeptide-1, etc.

Inquiry History

450 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Weight Loss Semaglutide intermediate 99% White powder COA High Quality peptide GLP-1 910463-68-2	5 MG	Apr 11, 2024
United States	Gene-Biocon Semaglutide 910463-68-2 GLP-1analogs diabetes weight loss 96% White or off-white powder	2	Dec 5, 2023
China	Semaglutide CAS 910463-68-2	1 KG	Apr 16, 2026
United States	Sermaglutide 99% 910463-68-2	2 KG	Oct 21, 2023
Sri Lanka	Bulk Supply 98% up Sermaglutide powder CAS 910463-68-2	300 G	Nov 18, 2023
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	60 MG	Aug 4, 2025
United Kingdom	TGYFactory Supply Semaglutide Peptide 99% CAS 910463-68-2	50 MT	Nov 13, 2023
United States	10MG vial pack Semaglutide 99% 910463-68-2 GLP-1 Peptide	10 MT	Oct 18, 2023
China	Semaglutide Tirzepatide for Weight Loss CAS: 910463-68-2 Retatrutide Cagrilintide	1 MT	Jul 5, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	10 MT	Sep 19, 2025
United States	High Purity IGF-1 LR3 Peptide CAS 910463-68-2 IGF1 LR3	2	Nov 13, 2024
United States	semaglutide CAS 910463-68-2 in stock 2-4 days safe delivery	1 MT	Nov 4, 2023
India	Best Price 99% Semaglutide Peptide 10mg Vials Semaglutide CAS 910463-68-2	100	Nov 8, 2023
United Kingdom	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	10 MT	Nov 14, 2023
Singapore	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	2 G	Nov 3, 2023
United States	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	100 MT	Oct 26, 2023
United States	GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2	1 MT	Oct 20, 2023
United States	99.9% Purity Semaglutide Petide 910463-68-2 For Type II diabetes mellitus Obesity	50 MT	Nov 11, 2023
United States	GLP-1 Injection Weight Loss Tirzepatide Semaglutide 99% Purity Peptides CAS: 910463-68-2	1 MT	Oct 25, 2023
United Kingdom	Manufacturer supply high purity Semaglutide 98% with best price cas 910463-68-2	10	Oct 19, 2023

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China origin pharmaceutical peptide Sermaglutide

Product Description

Seller Information