70% water-soluble azithromycin

The mechanism of action of azithromycin is similar to that of erythromycin in that it exerts an antibacterial effect by binding to the 50S subunit of the ribosomes of sensitive bacteria, inhibiting RNA-dependent protein synthesis, and retaining the antibacterial spectrum of typical erythromycin. The activity against chlamydia is similar to erythromycin. Compared with erythromycin, the antibacterial activity of gram-negative bacteria has been significantly improved, the antibacterial activity of influenza bacillus and Neisseria gonorrhoeae is more than 4 times stronger than erythromycin, the antibacterial activity of Legionella is about 2 times stronger than that of erythromycin, and the antibacterial activity of enterobacteriaceae is also significantly stronger than erythromycin. The MIC for most gram-negative bacteria was less than 1μg/ml. Staphylococcus aureus and Streptococcus pyogenes had cross-resistance to erythromycin. It also has good killing effect on toxoplasmosis and treponema pallidum. Azithromycin is mainly used for respiratory tract infection, urogenital tract infection, skin soft tissue infection and sexually transmitted diseases caused by sensitive microorganisms

Macrolide antimicrobials, nitrogen-containing heterocycles, have similar antibacterial mechanism to erythromycin, but have a wider antibacterial spectrum. The antibacterial activity against gram-positive bacteria is stronger, and the antibacterial activity against Gram-negative bacteria such as Haemophilus influenzae, Salmonella, Escherichia coli, shigella, etc., is also stronger. And stable to acid, good tolerance. It has good therapeutic effect on respiratory tract infection, skin soft tissue infection and sexually transmitted diseases caused by sensitive strains. It is used as an antibiotic for various infections caused by sensitive bacteria, such as respiratory system infections, skin and soft tissue infections. It is used for respiratory tract infections, urinary tract infections, skin and soft tissue infections and sexually transmitted diseases