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Ertapenem hydrochloride

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CAS No.:

153832-46-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ShangHai

Packaging:

bags

Price valid (until):

2024-04-01

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HANGZHOU TIANYE CHEMICALS CO., LTD

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Di-n-butyl naphthalene-2,6-dicarboxylate

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Ertapenem is another synthetic carbapenem with a rather complex side chain at C-3. It is used once daily parenterally, with special application against anaerobes. As with meropenem, the 4-β-methyl group confers stability toward dehydropeptidase-1 It is not active against pseudomonads or acinetobacteria and, therefore, should not be substituted for imipenem or meropenem. It is relatively strongly bound to serum proteins, so it has a prolonged half-life, making it more convenient to use than the other carbapenems when its spectrum warrants this. Its reported indications include complicated intra-abdominal and complicated skin/skin structure infections caused by sensitive organisms (for intra-abdominal: Escheri chia coli, Clostri di um clostri doforme, Bacteroi des fragilis, and Peptostreptococcus sp; for skin/skin structures: Staphylococcus aureus (methicillin-susceptible strains), Streptococcus pyogenes, E.coli, or Peptostreptococcus sp.). It can be administered once daily.

Items	Specifications
Boiling point	813.9±65.0 °C(Predicted)
density	1.55±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	soluble in DMSO, Methanol
pka	4.03±0.10(Predicted)
form	Foam
color	Brown

Basic Info

Product Name:

Ertapenem

Other Name:

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,3-[[(3S,5S)-5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-,(4R,5S,6S)-;1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid,3-[[5-[[(3-carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-,[4R-[3(3S*,5S*),4α,5β,6β(R*)]]-;(4R,5S,6S)-3-[[(3S,5S)-5-[[(3-Carboxyphenyl)amino]carbonyl]-3-pyrrolidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;Ertapenem

CAS No.:

153832-46-3

Molecular Formula:

C22H25N3O7S

InChIKeys:

InChIKey=JUZNIMUFDBIJCM-ANEDZVCMSA-N

Molecular Weight:

475.51

Exact Mass:

475.51

EC Number:

1533716-785-6

UNII:

G32F6EID2H

DSSTox ID:

DTXSID50165456

NCI Thesaurus Code:

C61752

ATC Code:

J01DH03|J - Antiinfectives for systemic use

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

182

XLogP3:

0.3

Density:

1.55±0.1 g/cm3(Predicted)

Boiling Point:

813.9±65.0 °C(Predicted)

Flash Point:

446.0±34.3 °C

Refractive Index:

1.700

Water Solubility:

soluble as sodium salt

Storage Conditions:

Do not store lyophilized powder above 25 deg C (77 deg F).

Vapor Pressure:

3.56X10-24 mm Hg at 25 deg C (est)

Henrys Law Constant:

Henry's Law constant = 7.68X10-29 atm-cu m/mol at 25 °C (est)

Experimental Properties:

White to off-white hygroscopic, weakly crystalline powder. Soluble in water, 0.9% sodium chloride solution. Practically insoluble in ethanol; insoluble in isopropyl acetate /Ertapenem sodium salt/|Insoluble in tetrahydrofuran /Ertapenem sodium/|Hydroxyl radical reaction rate constant = 1.69X10-10 cu cm/molec-sec at 25 °C (est)

See More Ertapenem Properties 

Hazard Identification

Classification of the substance or mixture

no data available

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	no data available
Signal word	no data available
Hazard statement(s)	no data available
Prevention	no data available
Response	no data available
Storage	no data available
Disposal	no data available

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Ertapenem Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Di-n-butyl naphthalene-2,6-dicarboxylate

Location:
1208# HuaCe Building-B,Wuchanggang Road,XIHU District,Hangzhou City,Zhejiang Province ,China

Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
15

Total Annual Revenue:
$5 million-$10 million

Total Employees:
5-10

Year of Establishment:
2023

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Ertapenem API 99% White powder	1 KG	Mar 1, 2024

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